要理解為何癌症會導致肌肉萎縮，其中的一道辦法就是對比萎縮肌肉與正常肌肉有甚麼分別，再以推敲其相關的機制。807Please respect copyright.ＰＥＮＡＮＡZH5iAVACwT
807Please respect copyright.ＰＥＮＡＮＡlBWFyRwnaR
807Please respect copyright.ＰＥＮＡＮＡ0mtACFuL93
(圖2)研究發現，患癌老鼠的萎縮肌肉中，其名為ZIP14的蛋白質含量特別高企，且在患癌的老鼠但其肌肉並沒有萎縮的情況下， ZIP14的蛋白質含量並沒有顯著提升。807Please respect copyright.ＰＥＮＡＮＡ5WylrbQJmC
807Please respect copyright.ＰＥＮＡＮＡHVxVY62aP6
807Please respect copyright.ＰＥＮＡＮＡtdTXC39XTH
(圖3)ZIP14蛋白質的主要作用是把鋅 (Zinc)輸送到細胞裡頭。807Please respect copyright.ＰＥＮＡＮＡ4wGT32xYI4
807Please respect copyright.ＰＥＮＡＮＡie3GoCbDUZ
807Please respect copyright.ＰＥＮＡＮＡGdFkmlxlkF
科學家量度因癌症而導致萎縮的肌肉，發現肌肉的鋅 (Zinc)含量的確是比正常肌肉的為多，與其ZIP14蛋白質含量不謀而合。807Please respect copyright.ＰＥＮＡＮＡ34oQWgeglf
807Please respect copyright.ＰＥＮＡＮＡPBpylT6LwH
807Please respect copyright.ＰＥＮＡＮＡ0kVcjf6tMy
(圖4)利用基因工程移除ZIP14蛋白質的話，可以見得到患癌老鼠的肌肉細胞橫切面並沒有顯著的減少。807Please respect copyright.ＰＥＮＡＮＡjhT8yadDgJ
807Please respect copyright.ＰＥＮＡＮＡMaXS6mP8e3
807Please respect copyright.ＰＥＮＡＮＡcuMYAhlGGH
再作一系列的實驗後，科學家推斷當癌細胞所釋出的TGFa/b物質到達肌肉位置後，便會引起肌肉ZIP14蛋白質含量上升，因而引起肌肉萎縮。807Please respect copyright.ＰＥＮＡＮＡjw2AbSIHRq
807Please respect copyright.ＰＥＮＡＮＡxidsGyPfOm
科學家們現正研究如何針對ZIP14蛋白質來抑制癌症所引致的肌肉萎縮，結果適目而待。807Please respect copyright.ＰＥＮＡＮＡXl4zTYB1uj
807Please respect copyright.ＰＥＮＡＮＡBA7BpreIsE
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。807Please respect copyright.ＰＥＮＡＮＡshlFNAVD8V
807Please respect copyright.ＰＥＮＡＮＡZ530uFkMEm
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc807Please respect copyright.ＰＥＮＡＮＡGlP0O4NF4y
807Please respect copyright.ＰＥＮＡＮＡSfYHZN20bB
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。807Please respect copyright.ＰＥＮＡＮＡt5qNbhb3SW
807Please respect copyright.ＰＥＮＡＮＡOP7V4sQou0
Link:807Please respect copyright.ＰＥＮＡＮＡaK9FyXWNYK
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio807Please respect copyright.ＰＥＮＡＮＡxtdgWUdRvF
807Please respect copyright.ＰＥＮＡＮＡesbgF5TiLe
807Please respect copyright.ＰＥＮＡＮＡ7R5fvEAOYw
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。807Please respect copyright.ＰＥＮＡＮＡbrkJV0uf04
807Please respect copyright.ＰＥＮＡＮＡUZ7x9O8unI
Ref1:https://pubmed.ncbi.nlm.nih.gov/29875463/807Please respect copyright.ＰＥＮＡＮＡO5opwB7bun
8964 copyright protection803ＰＥＮＡＮＡWoDTwqsgzu 維尼

216.73.216.228