科普專欄–薯不揀單 - 深入淺出–腸道細菌與大腸癌

腸道是細菌們聚居體內的其中一道地方，而腸道細菌品種的變異，將有助大腸癌的形成。751Please respect copyright.ＰＥＮＡＮＡPuMoml0jXq
751Please respect copyright.ＰＥＮＡＮＡxLg0yBVIYr
751Please respect copyright.ＰＥＮＡＮＡUYWXVqozlD
（圖2）糞便含有腸道的細菌，透過糞便移植(其中一方法為從口中灌入)，人類腸道的細菌亦因而能夠寄居到老鼠腸道中。751Please respect copyright.ＰＥＮＡＮＡYZKKqQRXLe
751Please respect copyright.ＰＥＮＡＮＡ5Rh1NCB61M
751Please respect copyright.ＰＥＮＡＮＡ0QutbVUdom
就此，有科學家嘗試將健康人士及腸癌病人的糞便移植到老鼠腸道中，探索腸道細菌對大腸癌的影響(Ref1)。751Please respect copyright.ＰＥＮＡＮＡP05a5r0Qy5
751Please respect copyright.ＰＥＮＡＮＡt4B7lR7Jwy
（圖3）從圖中可見，莫論是健康還是腸癌人士糞便組別也好，普通老鼠均不會出現腸癌。751Please respect copyright.ＰＥＮＡＮＡdo7O9dx6Ck
751Please respect copyright.ＰＥＮＡＮＡiQ8jU6ChWU
751Please respect copyright.ＰＥＮＡＮＡvXN2TqZMrR
但在天生容易生腸癌的老鼠中，移植腸癌人士糞便後所出現的腫瘤數量，明顯的比健康人士糞便組別為多。751Please respect copyright.ＰＥＮＡＮＡ4IQdy7oiAa
751Please respect copyright.ＰＥＮＡＮＡBjZ1F3NntN
（圖4）同時，移植腸癌人士糞便後所出現的腫瘤，體積亦明顯的比健康人士糞便組別為大。751Please respect copyright.ＰＥＮＡＮＡXn8jjCbtQt
751Please respect copyright.ＰＥＮＡＮＡbo0o62t8aR
751Please respect copyright.ＰＥＮＡＮＡ2Av3xRkdzi
而移植糞便後，兩組老鼠的腸道細菌品種亦有明顯分別。751Please respect copyright.ＰＥＮＡＮＡZPmKco1YTU
751Please respect copyright.ＰＥＮＡＮＡ1VDtSXAHcE
（圖5）重要的是，腸癌人士糞便中的某幾隻脂肪酸數量，亦明顯比健康人士糞便組別為少。751Please respect copyright.ＰＥＮＡＮＡfmjAaJgCdB
751Please respect copyright.ＰＥＮＡＮＡmNhMJu0zeg
751Please respect copyright.ＰＥＮＡＮＡbyL4ss1TuT
依照現時的理論，人體有部份的腸道細菌乃依靠消化食用纖維維生。751Please respect copyright.ＰＥＮＡＮＡmztQ5wRqjP
751Please respect copyright.ＰＥＮＡＮＡOknT3ZPiHA
當人體長期沒有進食纖維的話，將會導致腸道細菌品種失衡，使進食脂肪酸的細菌品種助大。751Please respect copyright.ＰＥＮＡＮＡVMyz0cEXN4
751Please respect copyright.ＰＥＮＡＮＡ42WFrHT9DW
這亦有可能解釋得到，為何腸癌人士糞便中某數款脂肪酸的數量亦相對之為少。751Please respect copyright.ＰＥＮＡＮＡ3khFI1qdre
751Please respect copyright.ＰＥＮＡＮＡjxvbzl0pZr
基於腸道細菌品種與大腸癌的形成有著密切關係，有不少研究團隊亦開始研究如何透過檢測糞便的細菌品種來推算出大腸癌的出現機率，與內窺鏡檢查相輔相成。751Please respect copyright.ＰＥＮＡＮＡpsEWAHxNBr
751Please respect copyright.ＰＥＮＡＮＡLxCVamsLMU
751Please respect copyright.ＰＥＮＡＮＡKbmqp9MLZP
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。751Please respect copyright.ＰＥＮＡＮＡDDMVnLaBt9
751Please respect copyright.ＰＥＮＡＮＡApQ1HhK4e1
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc751Please respect copyright.ＰＥＮＡＮＡZb4K3Wwo46
751Please respect copyright.ＰＥＮＡＮＡ9jMGlJYww0
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。751Please respect copyright.ＰＥＮＡＮＡO6jVJZ0ZuX
751Please respect copyright.ＰＥＮＡＮＡQD68OJOFoQ
Link:751Please respect copyright.ＰＥＮＡＮＡ6yU6JfxEL6
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio751Please respect copyright.ＰＥＮＡＮＡZs5GN1J7sf
751Please respect copyright.ＰＥＮＡＮＡQE6CPoBdfl
有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。751Please respect copyright.ＰＥＮＡＮＡHjsHbtuQ6P
751Please respect copyright.ＰＥＮＡＮＡRYPbjQBy66
https://www.instagram.com/potatopigtongue/751Please respect copyright.ＰＥＮＡＮＡuQSYKhsBKw
751Please respect copyright.ＰＥＮＡＮＡ0gE1F8QYHW
751Please respect copyright.ＰＥＮＡＮＡWaLuEtg8xx
Ref1:https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(19)30625-5/fulltext751Please respect copyright.ＰＥＮＡＮＡBrFmgs0iie

ns216.73.216.228da2

介面主題:

字體大小:

行距:

段距:

自動加載下一章