科普專欄–薯不揀單 - 深入淺出–武漢肺炎病毒D614G變種

武漢肺炎病毒現時的主流品種為D614G，一道較為簡易的說明方法就是原來的D614品種變異成為G614品種。591Please respect copyright.ＰＥＮＡＮＡmi9NEp9Kpa
591Please respect copyright.ＰＥＮＡＮＡOqtQafrY65
591Please respect copyright.ＰＥＮＡＮＡXxUGdJIFvY
而根據GISAID公開資料庫記錄，G614品種最先在1月24日的四川病毒樣本出現。591Please respect copyright.ＰＥＮＡＮＡq4esxJ5G4k
591Please respect copyright.ＰＥＮＡＮＡADmOZWekfM
（圖2）何解G614品種能夠成為主流，一直是科學家想解答的問題。591Please respect copyright.ＰＥＮＡＮＡxRNhzRbMhd
591Please respect copyright.ＰＥＮＡＮＡKX2hNrZYwm
591Please respect copyright.ＰＥＮＡＮＡPnk4xbZTIW
之前所獲得的實驗數據，大多是從病毒一小段的部份、或者是合成病毒獲取結果，沒能百分百反映現實。591Please respect copyright.ＰＥＮＡＮＡkjD0186lYH
591Please respect copyright.ＰＥＮＡＮＡWaSwNGFjGY
直至最近，才有科學家利用真實存在的武肺病毒進行實驗。591Please respect copyright.ＰＥＮＡＮＡOZzkLPL7b4
591Please respect copyright.ＰＥＮＡＮＡMX5esOdoFE
（圖3）在研究中（Ref1)，科學家將D614品種及G614品種以1 : 1的比例從倉鼠的鼻孔注入其體內。591Please respect copyright.ＰＥＮＡＮＡWSPxNN5H2z
591Please respect copyright.ＰＥＮＡＮＡ3mxlxSFLQ6
591Please respect copyright.ＰＥＮＡＮＡmUTnSOa4hR
如果最終G614品種/D614品種的比例大於1的話，亦即是代表G614品種在繁殖方面比D614品種更為優勝。591Please respect copyright.ＰＥＮＡＮＡzbWTRheXwS
591Please respect copyright.ＰＥＮＡＮＡg3YpHD7GBi
（圖4）倉鼠受病毒感染7日後，鼻孔、氣管及肺部個別區域的G614品種/D614品種均大於1，顯示G614品種在上述區域有著較佳的繁殖優勢。591Please respect copyright.ＰＥＮＡＮＡpb0MSMnCUj
591Please respect copyright.ＰＥＮＡＮＡMhEcUhsdZa
591Please respect copyright.ＰＥＮＡＮＡfdxv8dTBFp
同時在實驗室的人體肺部細胞中，就算用上D614品種及G614品種以9 : 1的比例方式感染，G614品種/D614品種在其後感染日子均呈大於1的狀態，更進一步顯示G614品種的繁殖優勢。591Please respect copyright.ＰＥＮＡＮＡTklZchzaPK
591Please respect copyright.ＰＥＮＡＮＡ0oV2PlPfue
591Please respect copyright.ＰＥＮＡＮＡsrL4rkxOgd
（圖5）科學家同時亦發現，G614品種的病毒在各種溫度上均比D614品種相對為穩定。591Please respect copyright.ＰＥＮＡＮＡuz1DiwvnXy
591Please respect copyright.ＰＥＮＡＮＡ0W87jppdhq
591Please respect copyright.ＰＥＮＡＮＡK1UKIy7mKq
不過好消息是，對抗D614品種的抗體，其對抗G614品種品種效率並無任何損傷。591Please respect copyright.ＰＥＮＡＮＡzzW09ZL3Ro
591Please respect copyright.ＰＥＮＡＮＡKyHMJIk4Q8
這亦即間接顯示出以D614品種作原材料的疫苗，其產生的抗體亦能有效對抗G614品種病毒，而事實上現今亦有疫苗是利用G614品種作原材料，奈何是鄰國出品。591Please respect copyright.ＰＥＮＡＮＡuuQvStXFGZ
591Please respect copyright.ＰＥＮＡＮＡ9kT7kS20LJ
591Please respect copyright.ＰＥＮＡＮＡIIsJOb73tH
（圖6）至於近來在挪威發現的新變種M439K品種，基於是新發現的關係，現時醫學界及學術界均無任何學術文章作詳細研究其特性。591Please respect copyright.ＰＥＮＡＮＡ2cOl1GTbVN
591Please respect copyright.ＰＥＮＡＮＡNeH8s4kaSc
591Please respect copyright.ＰＥＮＡＮＡNViLXpKJdu
莫論病毒變種與否，只需一個乞嗤，病毒就已經不需近距離接觸，便能透過體液傳播至他人。591Please respect copyright.ＰＥＮＡＮＡJfWGCmWXDF
591Please respect copyright.ＰＥＮＡＮＡWJRMbIQSjo
將「新變種」及「不需近距離接觸」串連在一起的報導手法，有著混淆視聽的成份，並不可取。591Please respect copyright.ＰＥＮＡＮＡp9BKbFvB8q
591Please respect copyright.ＰＥＮＡＮＡy54ryxdFsq
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。591Please respect copyright.ＰＥＮＡＮＡMOWJdRsKku
591Please respect copyright.ＰＥＮＡＮＡd2HjtjKqhY
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc591Please respect copyright.ＰＥＮＡＮＡQpwKyjkSmI
591Please respect copyright.ＰＥＮＡＮＡD8ukdMo5P0
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。591Please respect copyright.ＰＥＮＡＮＡQtmgIVWknX
591Please respect copyright.ＰＥＮＡＮＡatx5EIKA0K
Link:591Please respect copyright.ＰＥＮＡＮＡoRXgz9IUHH
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio591Please respect copyright.ＰＥＮＡＮＡMBioz2whuB
591Please respect copyright.ＰＥＮＡＮＡz0Nm5ZCcqH
591Please respect copyright.ＰＥＮＡＮＡpvHuYDVvb8
有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。591Please respect copyright.ＰＥＮＡＮＡ20kudQY3Os
591Please respect copyright.ＰＥＮＡＮＡyZxfDd42ri
https://www.instagram.com/potatopigtongue/591Please respect copyright.ＰＥＮＡＮＡOXGf73imqq
591Please respect copyright.ＰＥＮＡＮＡwYpzL658Ve
591Please respect copyright.ＰＥＮＡＮＡ4VbV6sLOwh
Ref1:https://www.nature.com/articles/s41586-020-2895-3591Please respect copyright.ＰＥＮＡＮＡ1uWwe9sOFx