科普專欄–薯不揀單 - 深入淺出–治理暗瘡的新方向

暗瘡對大部份人來說可謂是一道萬惡的存在，尤其是愛靚唔愛命的女士們的公敵。619Please respect copyright.ＰＥＮＡＮＡgFmvUjIAy3
619Please respect copyright.ＰＥＮＡＮＡDBuKtdhlkI
在講述暗瘡的形成之前，我們首先需要了解一下皮膚的背景資料。619Please respect copyright.ＰＥＮＡＮＡpPSoaQudBV
619Please respect copyright.ＰＥＮＡＮＡTs4efNsb7L
619Please respect copyright.ＰＥＮＡＮＡdDUB6RQgsC
（圖1）皮膚是人類最大的器官，它是我們一道抵禦外來物入侵的防線，同時亦提供了一個優良環境給予各式各樣的細菌及真菌成長及聚居。619Please respect copyright.ＰＥＮＡＮＡHqhZWdboud
619Please respect copyright.ＰＥＮＡＮＡgyNPra8dND
除皮膚表層外，那些細菌及真菌亦可聚居在髮囊、負責散熱的汗腺及負責分泌油脂的皮脂腺裡頭。619Please respect copyright.ＰＥＮＡＮＡurwqDQzM7L
619Please respect copyright.ＰＥＮＡＮＡ40NINiplI2
619Please respect copyright.ＰＥＮＡＮＡWUQhtIC3j7
619Please respect copyright.ＰＥＮＡＮＡ7Yd5UogFnS
（圖2）皮膚最外層的細胞全都是已死的細胞(Dead Cells)，學名為Enucleated keratinocytes。619Please respect copyright.ＰＥＮＡＮＡ2VF567XR7M
619Please respect copyright.ＰＥＮＡＮＡwI79pEij4o
這些已死的細胞會不斷脫落，大概每日總共會脫落50億這些已死的細胞，而下層已死的細胞會逐漸補上，日復如是。619Please respect copyright.ＰＥＮＡＮＡBDvoAnPlxV
619Please respect copyright.ＰＥＮＡＮＡNBn6Yd2VwI
619Please respect copyright.ＰＥＮＡＮＡz87ziz3cO2
619Please respect copyright.ＰＥＮＡＮＡDA7iVjupMd
（圖3）暗瘡的形成，與那些表層細胞有著莫大的關係。619Please respect copyright.ＰＥＮＡＮＡ1a8tPKx8F3
619Please respect copyright.ＰＥＮＡＮＡPYHd04C8Jb
以下為形式暗瘡的簡略三步曲：619Please respect copyright.ＰＥＮＡＮＡtbKFExnGDc
619Please respect copyright.ＰＥＮＡＮＡpsjXfdZNaT
1.皮膚表面已死細胞脫落到髮囊裡頭。619Please respect copyright.ＰＥＮＡＮＡ8ViHRO9VON
619Please respect copyright.ＰＥＮＡＮＡC9glkvpRVs
2.皮脂腺釋出油脂，因已死細胞阻窒通道，導致油脂無法離開，久而久之便成為黑頭。619Please respect copyright.ＰＥＮＡＮＡo1q6NMQMbU
619Please respect copyright.ＰＥＮＡＮＡgu1f0coPOL
3.聚居在油脂腺的細菌分解油脂為更簡單結構的油脂物，而這些油脂物觸動發炎反應，造就暗瘡的誕生。619Please respect copyright.ＰＥＮＡＮＡlbgOkR5HSc
619Please respect copyright.ＰＥＮＡＮＡGvL2O7LkmW
619Please respect copyright.ＰＥＮＡＮＡfI9lrQyKP5
619Please respect copyright.ＰＥＮＡＮＡfAQCzZYdEr
（圖4）青春期荷爾蒙作怪，油脂分泌特別旺盛，所以年青人特別容易生暗瘡。619Please respect copyright.ＰＥＮＡＮＡVxKS3rQ6n1
619Please respect copyright.ＰＥＮＡＮＡ8OIvzVK1BZ
但是，有些人就算做足日常護理都會特別容易生暗瘡，而有些不愛日常臉部護理的懶鬼就死都唔會生暗瘡，裡頭究竟是甚麼原因呢？619Please respect copyright.ＰＥＮＡＮＡbxJHIqPPYq
619Please respect copyright.ＰＥＮＡＮＡsKAV7QUwWs
619Please respect copyright.ＰＥＮＡＮＡAI2aYqdPi4
619Please respect copyright.ＰＥＮＡＮＡuEQXyrCWdx
（圖5）大量的研究指出，Cutibacterium acnes (C. acnes)是人體皮膚最常見且數量眾多的一種細菌，亦是暗瘡促成的元兇。619Please respect copyright.ＰＥＮＡＮＡ9FtW7KdOgw
619Please respect copyright.ＰＥＮＡＮＡeqR2Js0yKh
易生暗瘡以及不易生暗瘡的人，C. acnes 數量並沒有太大的分別，但品種上有著一道顯著的分別。619Please respect copyright.ＰＥＮＡＮＡgrcJVIbyr5
619Please respect copyright.ＰＥＮＡＮＡoAz0DzcwFq
易生暗瘡人皮膚上的C. acnes 品種更有效率代謝皮脂腺所釋出的油脂，亦即是更容易促成發炎反應形成暗瘡。619Please respect copyright.ＰＥＮＡＮＡvnJTKqhY5a
619Please respect copyright.ＰＥＮＡＮＡZ3ye1d4nZx
619Please respect copyright.ＰＥＮＡＮＡdrqsLMPA1q
619Please respect copyright.ＰＥＮＡＮＡVpDxxt7EJj
（圖6）現時治理暗瘡的手法大多會用上benzoyl peroxide或retinoic acid，目的是刺激皮膚及減低油脂的分泌。619Please respect copyright.ＰＥＮＡＮＡueLqvMKQq6
隨著科技的進步及對皮膚細菌的認識，科學界有著思想上的轉變，認為改變皮膚上的細菌群組才是對付暗瘡治標且治本的方法。619Please respect copyright.ＰＥＮＡＮＡnHUxYplKDm
619Please respect copyright.ＰＥＮＡＮＡ9D14dFBsYi
現時只至有三種治理暗瘡的嶄新手段正進行臨床階段之中。619Please respect copyright.ＰＥＮＡＮＡy8ehrs9paU
619Please respect copyright.ＰＥＮＡＮＡCqVq1CNTda
1.把不易生暗瘡的人皮膚表面上的C. acnes放到易生暗瘡人士上，企圖以良幣消除劣幣的方式取代舊有的C. acnes。619Please respect copyright.ＰＥＮＡＮＡ36MmhCFOIx
619Please respect copyright.ＰＥＮＡＮＡWRDQMjLzHV
2.把失去化謝油脂能力的C. acnes取代舊有的C. acnes。619Please respect copyright.ＰＥＮＡＮＡOiaoJ2aJZN
619Please respect copyright.ＰＥＮＡＮＡcKK0n26F3K
3.把懂得釋放抑制發炎化應化學物的C. acnes取代舊有的C. acnes。619Please respect copyright.ＰＥＮＡＮＡEZakJ6CXG5
619Please respect copyright.ＰＥＮＡＮＡJed653bOXy
今年的十月相信會有這些臨床研究的進一步結果的分析，但願這種治療方式會為暗瘡人士帶來一股新希望。619Please respect copyright.ＰＥＮＡＮＡ0DMgqh9Ffo
619Please respect copyright.ＰＥＮＡＮＡ5g8twOEP2u
619Please respect copyright.ＰＥＮＡＮＡVEGrLsqdLJ
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。619Please respect copyright.ＰＥＮＡＮＡZPKwONkPOl
619Please respect copyright.ＰＥＮＡＮＡBtJ33U8T9V
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc619Please respect copyright.ＰＥＮＡＮＡq7kpJ4hnrj
619Please respect copyright.ＰＥＮＡＮＡFgWE2AvIuN
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。619Please respect copyright.ＰＥＮＡＮＡkRGjh6moGS
619Please respect copyright.ＰＥＮＡＮＡMV71H2gCrY
Link:619Please respect copyright.ＰＥＮＡＮＡEpkyNGTo0y
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio619Please respect copyright.ＰＥＮＡＮＡo1NIWUex7D
619Please respect copyright.ＰＥＮＡＮＡwwBheF4t74
619Please respect copyright.ＰＥＮＡＮＡ7ZhRKADxKa
有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。