2018年3月，前俄羅斯間謀Sergei Skripai及其女兒在英國被人下毒，毒藥被證實為蘇聯在冷戰時期所研發的神經毒素Novichok。887Please respect copyright.ＰＥＮＡＮＡ0O4ZsZAFRi
887Please respect copyright.ＰＥＮＡＮＡNZ3cIwtjtU
2020年8月20日，一名極力反對普京的社會領袖Alexei Navalny，亦遭受到同類型的毒素傷害，表面證據暫時相信為被人在茶裡下毒。887Please respect copyright.ＰＥＮＡＮＡtebk8nHTAO
887Please respect copyright.ＰＥＮＡＮＡIsZxZvgW3d
本篇深入淺出，將會簡述神經系統的運作，以及神經毒素Novichok的機制。887Please respect copyright.ＰＥＮＡＮＡEZYIan8rpl
887Please respect copyright.ＰＥＮＡＮＡLjmXLk9jgn
887Please respect copyright.ＰＥＮＡＮＡkIbUcetHFY
887Please respect copyright.ＰＥＮＡＮＡMg1BdKnhly
（圖1）神經線負責傳遞信息，為身體內的橋樑。橋樑並不是緊密相扣著的，一條神經線質另一條神經線互相均有著一道空隙。887Please respect copyright.ＰＥＮＡＮＡvfklBRCYZq
887Please respect copyright.ＰＥＮＡＮＡC4Fn93PhYl
887Please respect copyright.ＰＥＮＡＮＡHlZCgTdS7E
887Please respect copyright.ＰＥＮＡＮＡr7hJoPv1An
887Please respect copyright.ＰＥＮＡＮＡnLr3NHJWhZ
（圖2）訊息在神經線中主要是以電流的方式傳遞。887Please respect copyright.ＰＥＮＡＮＡ0znUXHAgY7
887Please respect copyright.ＰＥＮＡＮＡgD1cLJItnc
電流來到神經線A的末端後，便會觸發ACh釋出，使ACh來到神經線之間的空隙。887Please respect copyright.ＰＥＮＡＮＡpUr0hTLHRk
887Please respect copyright.ＰＥＮＡＮＡbwlGquqeTX
ACh與另一神經線的Receptor結合後，便會觸發新一道的電流產生，使訊息一直能傳遞到終點。887Please respect copyright.ＰＥＮＡＮＡoyXG5vmLub
887Please respect copyright.ＰＥＮＡＮＡFVgO2Uk3hD
887Please respect copyright.ＰＥＮＡＮＡwVnpzPRqez
887Please respect copyright.ＰＥＮＡＮＡBPuGy3AwQM
887Please respect copyright.ＰＥＮＡＮＡrKyQ2iAhrz
（圖3）神經線空隙的AChE負責分解ACh，以免電流長期持續產生。887Please respect copyright.ＰＥＮＡＮＡOKHUD6dA3J
887Please respect copyright.ＰＥＮＡＮＡqw3qY6FJ1v
而俄國最愛的神經毒素Novichok則會與AChE合併及抑制AChE的功能，導致ACh不會被分解，使ACh無了期與神經線的Receptor結合，長期產生神經線電流的傳播，導致患者出現抽搐、癲癇等症狀，沒能適時治療的話更會導致死亡。887Please respect copyright.ＰＥＮＡＮＡmaiMVABRjV
887Please respect copyright.ＰＥＮＡＮＡhEUvYc9Pul
解毒劑暫時有幾種，Atropine能阻截ACh與Receptor合併，Pralidoxime能夠促使Novichok無法與AChE結合。887Please respect copyright.ＰＥＮＡＮＡSzaOAPRE0a
887Please respect copyright.ＰＥＮＡＮＡmCHOUNJEsC
這些解毒劑雖然可以使患者康復起來，但患者的認知及肌肉功大有可能會有收到永久性的損害。887Please respect copyright.ＰＥＮＡＮＡYrBlBgwf1f
887Please respect copyright.ＰＥＮＡＮＡgeS9OlrMqd
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。887Please respect copyright.ＰＥＮＡＮＡ1jXizIQvqj
887Please respect copyright.ＰＥＮＡＮＡeJpu02oXLJ
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc887Please respect copyright.ＰＥＮＡＮＡzh726m4VRQ
887Please respect copyright.ＰＥＮＡＮＡpCIoPKyXOO
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。887Please respect copyright.ＰＥＮＡＮＡ1BfwHA0p9P
887Please respect copyright.ＰＥＮＡＮＡ5t8xOHvMdx
Link:887Please respect copyright.ＰＥＮＡＮＡe1YI7nz9Pq
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio887Please respect copyright.ＰＥＮＡＮＡmx6LviboV5
887Please respect copyright.ＰＥＮＡＮＡMarL2nSXZF
887Please respect copyright.ＰＥＮＡＮＡSgBEaCc0j6
有興趣接收科普資訊的話，歡迎follow IG: potatopigtongue。887Please respect copyright.ＰＥＮＡＮＡFs83R2uOoA
8964 copyright protection883ＰＥＮＡＮＡjCQo5PwtHW 維尼

172.71.255.28