當細胞不斷累積不同數量及數目的基因變異,而細胞又沒能修復其變異的話,癌細胞便有機會形成。871Please respect copyright.PENANAs3Q2GHwBSz
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隨著我們的年紀遞增,細胞修復基因變異的能力亦會順之減弱,因此年紀越大,患癌的機率亦會越高。871Please respect copyright.PENANAC42BS4UcI2
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(圖2)科學家一直致力研究,希望能找出哪一些的基因變異會導致癌細胞的形成。871Please respect copyright.PENANA2ohph8WT4J
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在治療癌症的角度來看,當某特定的基因出現變異後,細胞所運行的機制便會與正常細胞所運行的有所不同。871Please respect copyright.PENANASpGUfTM8UI
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若我們能對症下藥針對其癌細胞所運行的變異機制,而其變異機制同時亦是癌細胞生存的救命草的話,那便會是一道非常有效消滅癌症的手法。871Please respect copyright.PENANAJi1RZOq8LR
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現今最為成功的例子為口服藥物Gleevec,詳情可參考延伸閱讀。871Please respect copyright.PENANAJ9Fpe4kavy
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延伸閱讀:https://lihkg.com/thread/2153898/page/1871Please respect copyright.PENANARzgQhsOSp7
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(圖3)圖中為老鼠小腸細胞的圖片,藍色區域為細胞核,紅色區域為發生對應基因變異的細胞,而白色區域則為正在進行自我複雜程序的細胞。871Please respect copyright.PENANAktJ2DzjAgi
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透過計算有多少細胞(對比紅白藍區域)正在進行自我繁殖的工序,科學家便能夠推敲那一款基因的變異將有助癌細胞生長。871Please respect copyright.PENANAmVA1coNEKw
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此為序章,下集將會更深入癌細胞基因變異後對周遭帶來的禍害。871Please respect copyright.PENANAhJ7uteUc44
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如果想我快啲出文的話,請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark,這對我非常之重要。871Please respect copyright.PENANATILMPepzVy
871Please respect copyright.PENANAcgwGAnxnZs
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc871Please respect copyright.PENANA8FDzB2RDLR
871Please respect copyright.PENANApVUoxgL0zp
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」,以課金的方式推動我繼續搜羅資料寫文,多謝。871Please respect copyright.PENANAcj9fLuA3vq
871Please respect copyright.PENANAUNKswLMx3a
Link:871Please respect copyright.PENANAFZwtdwmxWM
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio871Please respect copyright.PENANAyAPyCfUPBC
871Please respect copyright.PENANAwBp2FY2cEI
871Please respect copyright.PENANAnEZyqtWACV
除非Facebook及IG重開侵侵的account,否則我的IG將不會再作更新,只會寄居本土LIHKG及Penana。871Please respect copyright.PENANApjAABVi91F
871Please respect copyright.PENANAxQ5mdQRkV3
Ref1:https://www.nature.com/articles/s41586-021-03605-0871Please respect copyright.PENANAMRUs8CS1bY
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科普專欄–薯不揀單
Author:
薯仔聞茱莉
ISSUE #243
三十秒科學–基因突變對細胞的影響力(一)
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