科普專欄–薯不揀單 - 三十秒科學–癌細胞也會自肥？

從圖中可見，癌細胞所在的環境非常複雜。573Please respect copyright.ＰＥＮＡＮＡVo49II5riz
癌細胞附近不只有著各種細胞，其就近的血管大多處於參差不齊的狀態，導致營養及氧氣難以順利到達癌細胞裡頭。573Please respect copyright.ＰＥＮＡＮＡ6nn1VdX1CJ
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在這種「逆境」之中，癌細胞究竟有何手段求生呢?573Please respect copyright.ＰＥＮＡＮＡColtP1vGCC
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(圖2)在導管胰腺癌中，科學家發現癌細胞的所在位置含有大量名為CAM的細胞。573Please respect copyright.ＰＥＮＡＮＡ194Db4SN6D
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經一系列的研究後，科學家發現這些細胞竟然是協助癌細胞長大的好幫手。573Please respect copyright.ＰＥＮＡＮＡcoUfbVG9jU
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(圖3)圖中為癌細胞如何利用周遭的CAM細胞供養自己的機制。573Please respect copyright.ＰＥＮＡＮＡElf2Z1GLSx

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在營養短缺的環境下，癌細胞迫使周遭的細胞分解蛋白質供自己所用，從而渡過難關及繼續在逆境中成長。573Please respect copyright.ＰＥＮＡＮＡj54P1PVrZN
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在老鼠的動物模型中，若然抑制CAM細胞進行自噬作用，癌細胞的體積的確是有所縮小，得以證實癌細胞會用盡身邊的一事一物從而壯大自己，在先天資源短缺的環境下亦能「自肥」。573Please respect copyright.ＰＥＮＡＮＡdgrr5LhmCV
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如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。573Please respect copyright.ＰＥＮＡＮＡPsqrpPqdRZ
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc573Please respect copyright.ＰＥＮＡＮＡB3XueQsowi
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https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio573Please respect copyright.ＰＥＮＡＮＡKcPb005z3J
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Ref1:https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(17)30102-2573Please respect copyright.ＰＥＮＡＮＡCtxg6PVhr2
Ref2:https://pubmed.ncbi.nlm.nih.gov/27509858/573Please respect copyright.ＰＥＮＡＮＡxjzxSWMxVj

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