藥物的效用有時候因人而異，其中一道原因，可以歸究於每個人體內的腸道細菌品種有所不同所致。696Please respect copyright.ＰＥＮＡＮＡah8pKdYvZP
696Please respect copyright.ＰＥＮＡＮＡ8sjyOp7lgw
696Please respect copyright.ＰＥＮＡＮＡxOuj026JCf
(圖2)口服藥物要抵達血管循環系統的話，無可避免將會途經我們的腸道。696Please respect copyright.ＰＥＮＡＮＡlNtqo4RXes
而我們腸道的細菌有能力改造或代謝藥物，因而改變藥物結構及其效用。696Please respect copyright.ＰＥＮＡＮＡbAJw9L4IkJ
696Please respect copyright.ＰＥＮＡＮＡ7GSx9qJLrY
696Please respect copyright.ＰＥＮＡＮＡSNVRF8ZnnA
696Please respect copyright.ＰＥＮＡＮＡtwlvLr7dvO
696Please respect copyright.ＰＥＮＡＮＡXocw1Rlhtv
(圖3)有科學家找來人體最為常見的76種腸道細菌品種，與271款不同界別常用的藥物共同放在一起12小時。696Please respect copyright.ＰＥＮＡＮＡU03Ns9X4Bi
696Please respect copyright.ＰＥＮＡＮＡjG5Q9UNEpi
696Please respect copyright.ＰＥＮＡＮＡMhFet74JKw
最終發現，271款藥物中，有多達176款藥物的濃度在被至少一種腸道細菌影響下，濃度減少了20%;696Please respect copyright.ＰＥＮＡＮＡDH5TWuZXDR
而這些腸道細菌品種每款可以代謝11-95款藥物不等。696Please respect copyright.ＰＥＮＡＮＡ0WUqzYLGN1
696Please respect copyright.ＰＥＮＡＮＡDjrLp31ifM
用上老鼠作動物模型，科學家更能找出所屬細菌哪一條基因負責消化/代謝藥物，引證腸道細菌影響藥物吸收的理念。696Please respect copyright.ＰＥＮＡＮＡ3svLe7YE3j
696Please respect copyright.ＰＥＮＡＮＡ0dHXZko20D
倘若你腸道恰巧住有細菌A，而細菌A又有能力吸收你所口服的藥物，那麼藥效便有可能會大大減低。696Please respect copyright.ＰＥＮＡＮＡAUd50bfVYg
696Please respect copyright.ＰＥＮＡＮＡbao1pbv5BB
血液注射而非口服的藥物將有機會不受此限，因為藥物並不需一定要經過腸道裡頭。696Please respect copyright.ＰＥＮＡＮＡpzntkNcI0u
696Please respect copyright.ＰＥＮＡＮＡqCOh5CA3zE
696Please respect copyright.ＰＥＮＡＮＡGD1Gd9QWfl
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。696Please respect copyright.ＰＥＮＡＮＡBEH8Qq0rT2
696Please respect copyright.ＰＥＮＡＮＡlSq3i8dE7f
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc696Please respect copyright.ＰＥＮＡＮＡQ8570byuLK
696Please respect copyright.ＰＥＮＡＮＡGk5RIaPwYI
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。696Please respect copyright.ＰＥＮＡＮＡnHGTBqIPc9
696Please respect copyright.ＰＥＮＡＮＡcImeEtZifk
Link:696Please respect copyright.ＰＥＮＡＮＡ2teq8I8Gqf
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio696Please respect copyright.ＰＥＮＡＮＡKWrYRRX678
696Please respect copyright.ＰＥＮＡＮＡcmJkE8JcfR
696Please respect copyright.ＰＥＮＡＮＡpDRh6MiC9k
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。696Please respect copyright.ＰＥＮＡＮＡclJK5xQpx5
696Please respect copyright.ＰＥＮＡＮＡpmfFSwoQvd
Ref1:https://www.nature.com/articles/s41586-019-1291-3696Please respect copyright.ＰＥＮＡＮＡKyheEanm4I
1234 copyright protection692ＰＥＮＡＮＡmPJjfk9xIV 尼

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