科普專欄–薯不揀單 - 三十秒科學–透視癌細胞

癌細胞轉移，即是從原來的位置轉移到另一地方。425Please respect copyright.ＰＥＮＡＮＡ8J6yq4UG7F
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利用老鼠作為癌細胞轉移研究的話，科學家又是如何得知癌細胞是否有出現轉移的過程，以及所轉移的地方呢?425Please respect copyright.ＰＥＮＡＮＡO4C9gNJfZZ
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（圖2）探知癌細胞轉移而又不需殺害老鼠的其中一道手段，就是藉助螢火蟲的螢光素酶幫助。425Please respect copyright.ＰＥＮＡＮＡuK0fHHAaKL
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螢光素酶(Luciferase)能夠將螢光素(Luciferin)轉化成為另一物質，同時亦會發出螢光。425Please respect copyright.ＰＥＮＡＮＡIDo9v81WfN
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換句話說，利用分子生物學技術強迫癌細胞表達螢光素酶的話，當他們遇上螢光素的時候，便會在其所在的位置發出螢光。425Please respect copyright.ＰＥＮＡＮＡqhewng6Lo8
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（圖3）往老鼠移植含螢光素酶的癌細胞，到達需要進行研究時間的時候便為牠們注射Luciferin，Luciferin會經由血液循環系統走遍全身，過一段時間後再對牠們進行麻醉，並用儀器探測螢光，便可以得知癌細胞的大小及所在位置。425Please respect copyright.ＰＥＮＡＮＡhN2AyvoVOC
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將右圖對比左圖，便可清晰得知右圖的癌細胞出現了轉移。將此螢光方法配合藥物或基因改造手段，便可得知所對應的醫學方法能否修成正果。425Please respect copyright.ＰＥＮＡＮＡOa8rZ6WCDb
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如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。425Please respect copyright.ＰＥＮＡＮＡdo4V6zKTo8
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc425Please respect copyright.ＰＥＮＡＮＡUUlyn8VjST
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。425Please respect copyright.ＰＥＮＡＮＡU8a4nXNqd3
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https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio425Please respect copyright.ＰＥＮＡＮＡFOxIzrFplP
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除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。425Please respect copyright.ＰＥＮＡＮＡVb1PJo31hh
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Ref1:https://pubmed.ncbi.nlm.nih.gov/27974793/425Please respect copyright.ＰＥＮＡＮＡB8Qir8AtSD

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