科普專欄–薯不揀單 - 深入淺出–腸道細菌與大腸癌

腸道是細菌們聚居體內的其中一道地方，而腸道細菌品種的變異，將有助大腸癌的形成。686Please respect copyright.ＰＥＮＡＮＡbb4b3fkfqJ
686Please respect copyright.ＰＥＮＡＮＡyT2oeGrAN6
686Please respect copyright.ＰＥＮＡＮＡgYiXrs91uC
（圖2）糞便含有腸道的細菌，透過糞便移植(其中一方法為從口中灌入)，人類腸道的細菌亦因而能夠寄居到老鼠腸道中。686Please respect copyright.ＰＥＮＡＮＡZVcw2Paj7f
686Please respect copyright.ＰＥＮＡＮＡ1FLknHjlD0
686Please respect copyright.ＰＥＮＡＮＡIKbouLdDpU
就此，有科學家嘗試將健康人士及腸癌病人的糞便移植到老鼠腸道中，探索腸道細菌對大腸癌的影響(Ref1)。686Please respect copyright.ＰＥＮＡＮＡVFIPW2zQx1
686Please respect copyright.ＰＥＮＡＮＡHI8ta3Ha6N
（圖3）從圖中可見，莫論是健康還是腸癌人士糞便組別也好，普通老鼠均不會出現腸癌。686Please respect copyright.ＰＥＮＡＮＡijtfwKR3t5
686Please respect copyright.ＰＥＮＡＮＡxKZttkwXzm
686Please respect copyright.ＰＥＮＡＮＡvgenffI2hV
但在天生容易生腸癌的老鼠中，移植腸癌人士糞便後所出現的腫瘤數量，明顯的比健康人士糞便組別為多。686Please respect copyright.ＰＥＮＡＮＡ4f2e7sxoGN
686Please respect copyright.ＰＥＮＡＮＡIEMNZGhIXx
（圖4）同時，移植腸癌人士糞便後所出現的腫瘤，體積亦明顯的比健康人士糞便組別為大。686Please respect copyright.ＰＥＮＡＮＡvLup02SyMH
686Please respect copyright.ＰＥＮＡＮＡOCl2z4yQIU
686Please respect copyright.ＰＥＮＡＮＡQG82kWS8cY
而移植糞便後，兩組老鼠的腸道細菌品種亦有明顯分別。686Please respect copyright.ＰＥＮＡＮＡv8neF52lgV
686Please respect copyright.ＰＥＮＡＮＡDhTAkInm08
（圖5）重要的是，腸癌人士糞便中的某幾隻脂肪酸數量，亦明顯比健康人士糞便組別為少。686Please respect copyright.ＰＥＮＡＮＡGtLDHUOYjt
686Please respect copyright.ＰＥＮＡＮＡFBTDCDy6RH
686Please respect copyright.ＰＥＮＡＮＡY5niIDeyeD
依照現時的理論，人體有部份的腸道細菌乃依靠消化食用纖維維生。686Please respect copyright.ＰＥＮＡＮＡh7O59VWQh5
686Please respect copyright.ＰＥＮＡＮＡc4EUnl0vhi
當人體長期沒有進食纖維的話，將會導致腸道細菌品種失衡，使進食脂肪酸的細菌品種助大。686Please respect copyright.ＰＥＮＡＮＡgAmJpG9RnJ
686Please respect copyright.ＰＥＮＡＮＡlse1YJLzmV
這亦有可能解釋得到，為何腸癌人士糞便中某數款脂肪酸的數量亦相對之為少。686Please respect copyright.ＰＥＮＡＮＡeG72Ry2Pig
686Please respect copyright.ＰＥＮＡＮＡ09JCr2Wr46
基於腸道細菌品種與大腸癌的形成有著密切關係，有不少研究團隊亦開始研究如何透過檢測糞便的細菌品種來推算出大腸癌的出現機率，與內窺鏡檢查相輔相成。686Please respect copyright.ＰＥＮＡＮＡteeQMWuD1Q
686Please respect copyright.ＰＥＮＡＮＡdsHffULzL9
686Please respect copyright.ＰＥＮＡＮＡ7hpLOzDXry
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。686Please respect copyright.ＰＥＮＡＮＡQ50xj8VvIJ
686Please respect copyright.ＰＥＮＡＮＡgQYjnhz1b7
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc686Please respect copyright.ＰＥＮＡＮＡWWs0BPivFU
686Please respect copyright.ＰＥＮＡＮＡIXA2aJBWLQ
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。686Please respect copyright.ＰＥＮＡＮＡcimProiQmk
686Please respect copyright.ＰＥＮＡＮＡaHxsEgvkjw
Link:686Please respect copyright.ＰＥＮＡＮＡfxEAPRqJ6U
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio686Please respect copyright.ＰＥＮＡＮＡMAWoyfieQB
686Please respect copyright.ＰＥＮＡＮＡCIWiG1xLP5
有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。686Please respect copyright.ＰＥＮＡＮＡXEPCi2MqX8
686Please respect copyright.ＰＥＮＡＮＡzjqt0OPnYG
https://www.instagram.com/potatopigtongue/686Please respect copyright.ＰＥＮＡＮＡd8hHHisytc
686Please respect copyright.ＰＥＮＡＮＡVGzR07CxJT
686Please respect copyright.ＰＥＮＡＮＡFSLs61K6oV
Ref1:https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(19)30625-5/fulltext686Please respect copyright.ＰＥＮＡＮＡrOpEcZfMjd

ns216.73.216.151da2

介面主題:

字體大小:

行距:

段距:

自動加載下一章