科普專欄–薯不揀單 - 深入淺出–武漢肺炎病毒D614G變種

武漢肺炎病毒現時的主流品種為D614G，一道較為簡易的說明方法就是原來的D614品種變異成為G614品種。599Please respect copyright.ＰＥＮＡＮＡV4yPsK1i6A
599Please respect copyright.ＰＥＮＡＮＡ9lkZQHpagz
599Please respect copyright.ＰＥＮＡＮＡObYvvGU4dm
而根據GISAID公開資料庫記錄，G614品種最先在1月24日的四川病毒樣本出現。599Please respect copyright.ＰＥＮＡＮＡSmn5xyjBKS
599Please respect copyright.ＰＥＮＡＮＡiD6kU9OWG8
（圖2）何解G614品種能夠成為主流，一直是科學家想解答的問題。599Please respect copyright.ＰＥＮＡＮＡSyqrl7063E
599Please respect copyright.ＰＥＮＡＮＡP7DBzomg43
599Please respect copyright.ＰＥＮＡＮＡlgkWNAkXjt
之前所獲得的實驗數據，大多是從病毒一小段的部份、或者是合成病毒獲取結果，沒能百分百反映現實。599Please respect copyright.ＰＥＮＡＮＡpXVBv1rziM
599Please respect copyright.ＰＥＮＡＮＡEAjehrzmWQ
直至最近，才有科學家利用真實存在的武肺病毒進行實驗。599Please respect copyright.ＰＥＮＡＮＡPRGN0SyPJf
599Please respect copyright.ＰＥＮＡＮＡCyJzD0V5O6
（圖3）在研究中（Ref1)，科學家將D614品種及G614品種以1 : 1的比例從倉鼠的鼻孔注入其體內。599Please respect copyright.ＰＥＮＡＮＡfmeMR9nEti
599Please respect copyright.ＰＥＮＡＮＡQ8wQiRbWbb
599Please respect copyright.ＰＥＮＡＮＡPsy6mkeCG2
如果最終G614品種/D614品種的比例大於1的話，亦即是代表G614品種在繁殖方面比D614品種更為優勝。599Please respect copyright.ＰＥＮＡＮＡ3tsLZddMC2
599Please respect copyright.ＰＥＮＡＮＡUu9q73a1n3
（圖4）倉鼠受病毒感染7日後，鼻孔、氣管及肺部個別區域的G614品種/D614品種均大於1，顯示G614品種在上述區域有著較佳的繁殖優勢。599Please respect copyright.ＰＥＮＡＮＡAoxAOjW4Qf
599Please respect copyright.ＰＥＮＡＮＡEN77cW5Jby
599Please respect copyright.ＰＥＮＡＮＡ04IcQwafjn
同時在實驗室的人體肺部細胞中，就算用上D614品種及G614品種以9 : 1的比例方式感染，G614品種/D614品種在其後感染日子均呈大於1的狀態，更進一步顯示G614品種的繁殖優勢。599Please respect copyright.ＰＥＮＡＮＡGl0WHTooqW
599Please respect copyright.ＰＥＮＡＮＡl1Jo0NmEb9
599Please respect copyright.ＰＥＮＡＮＡsJQmdxAd43
（圖5）科學家同時亦發現，G614品種的病毒在各種溫度上均比D614品種相對為穩定。599Please respect copyright.ＰＥＮＡＮＡASVWrIcWGF
599Please respect copyright.ＰＥＮＡＮＡzx6SsGmNoP
599Please respect copyright.ＰＥＮＡＮＡ07K3aQ6beW
不過好消息是，對抗D614品種的抗體，其對抗G614品種品種效率並無任何損傷。599Please respect copyright.ＰＥＮＡＮＡY4hOswngGV
599Please respect copyright.ＰＥＮＡＮＡoEMlnqxkB3
這亦即間接顯示出以D614品種作原材料的疫苗，其產生的抗體亦能有效對抗G614品種病毒，而事實上現今亦有疫苗是利用G614品種作原材料，奈何是鄰國出品。599Please respect copyright.ＰＥＮＡＮＡe2Te8ITq6E
599Please respect copyright.ＰＥＮＡＮＡnJxsMZoulK
599Please respect copyright.ＰＥＮＡＮＡXKqEqZCdXs
（圖6）至於近來在挪威發現的新變種M439K品種，基於是新發現的關係，現時醫學界及學術界均無任何學術文章作詳細研究其特性。599Please respect copyright.ＰＥＮＡＮＡ92GwpDRxNa
599Please respect copyright.ＰＥＮＡＮＡjZatX7buzG
599Please respect copyright.ＰＥＮＡＮＡZnHbLBMOpz
莫論病毒變種與否，只需一個乞嗤，病毒就已經不需近距離接觸，便能透過體液傳播至他人。599Please respect copyright.ＰＥＮＡＮＡd4ibGlVEOO
599Please respect copyright.ＰＥＮＡＮＡUJddNyDxeI
將「新變種」及「不需近距離接觸」串連在一起的報導手法，有著混淆視聽的成份，並不可取。599Please respect copyright.ＰＥＮＡＮＡlEsJHeklqi
599Please respect copyright.ＰＥＮＡＮＡ4MtiriYPUw
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。599Please respect copyright.ＰＥＮＡＮＡx81IoennIA
599Please respect copyright.ＰＥＮＡＮＡUjBxGqs50m
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc599Please respect copyright.ＰＥＮＡＮＡ3ENGVr6m11
599Please respect copyright.ＰＥＮＡＮＡOO0Bm8EzZx
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。599Please respect copyright.ＰＥＮＡＮＡonHssXERaY
599Please respect copyright.ＰＥＮＡＮＡjYKl4aMUAm
Link:599Please respect copyright.ＰＥＮＡＮＡeZLJHcKEoR
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio599Please respect copyright.ＰＥＮＡＮＡSu06Euda11
599Please respect copyright.ＰＥＮＡＮＡIBudzMaCzl
599Please respect copyright.ＰＥＮＡＮＡaVObjw2P1i
有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。599Please respect copyright.ＰＥＮＡＮＡbSZPeDeUoA
599Please respect copyright.ＰＥＮＡＮＡ6VEdaF72F5
https://www.instagram.com/potatopigtongue/599Please respect copyright.ＰＥＮＡＮＡlaFyFptD3X
599Please respect copyright.ＰＥＮＡＮＡS9OefMltHV
599Please respect copyright.ＰＥＮＡＮＡ5uLZJN6pVG
Ref1:https://www.nature.com/articles/s41586-020-2895-3599Please respect copyright.ＰＥＮＡＮＡGwPA8EYGJb