科普專欄–薯不揀單 - 深入淺出–武漢肺炎病毒D614G變種

武漢肺炎病毒現時的主流品種為D614G，一道較為簡易的說明方法就是原來的D614品種變異成為G614品種。854Please respect copyright.ＰＥＮＡＮＡyw2S8b0beg
854Please respect copyright.ＰＥＮＡＮＡyplACIG9HK
854Please respect copyright.ＰＥＮＡＮＡ2NsVJKc0bj
而根據GISAID公開資料庫記錄，G614品種最先在1月24日的四川病毒樣本出現。854Please respect copyright.ＰＥＮＡＮＡ08PKdlbPmr
854Please respect copyright.ＰＥＮＡＮＡ1ac3iQJzlr
（圖2）何解G614品種能夠成為主流，一直是科學家想解答的問題。854Please respect copyright.ＰＥＮＡＮＡYA22Znk3H6
854Please respect copyright.ＰＥＮＡＮＡZR5IPOFHuf
854Please respect copyright.ＰＥＮＡＮＡUTBXvlhk9E
之前所獲得的實驗數據，大多是從病毒一小段的部份、或者是合成病毒獲取結果，沒能百分百反映現實。854Please respect copyright.ＰＥＮＡＮＡ4Qv2Uqx69n
854Please respect copyright.ＰＥＮＡＮＡu5yUcBKtiO
直至最近，才有科學家利用真實存在的武肺病毒進行實驗。854Please respect copyright.ＰＥＮＡＮＡJA12sccESU
854Please respect copyright.ＰＥＮＡＮＡXq0o10b3aY
（圖3）在研究中（Ref1)，科學家將D614品種及G614品種以1 : 1的比例從倉鼠的鼻孔注入其體內。854Please respect copyright.ＰＥＮＡＮＡvyq5C7cA2I
854Please respect copyright.ＰＥＮＡＮＡ5sUcrLZ9yB
854Please respect copyright.ＰＥＮＡＮＡW9NJxTkTFM
如果最終G614品種/D614品種的比例大於1的話，亦即是代表G614品種在繁殖方面比D614品種更為優勝。854Please respect copyright.ＰＥＮＡＮＡPuVqGp5rND
854Please respect copyright.ＰＥＮＡＮＡTc0mWUiUhA
（圖4）倉鼠受病毒感染7日後，鼻孔、氣管及肺部個別區域的G614品種/D614品種均大於1，顯示G614品種在上述區域有著較佳的繁殖優勢。854Please respect copyright.ＰＥＮＡＮＡraU58TNPf7
854Please respect copyright.ＰＥＮＡＮＡPdjl6T2v32
854Please respect copyright.ＰＥＮＡＮＡeG6VbvoAQo
同時在實驗室的人體肺部細胞中，就算用上D614品種及G614品種以9 : 1的比例方式感染，G614品種/D614品種在其後感染日子均呈大於1的狀態，更進一步顯示G614品種的繁殖優勢。854Please respect copyright.ＰＥＮＡＮＡeOejcJW2tz
854Please respect copyright.ＰＥＮＡＮＡtrmeAkDxXO
854Please respect copyright.ＰＥＮＡＮＡi2DqMiW8yW
（圖5）科學家同時亦發現，G614品種的病毒在各種溫度上均比D614品種相對為穩定。854Please respect copyright.ＰＥＮＡＮＡX2LbJLAJmy
854Please respect copyright.ＰＥＮＡＮＡXXko6TzwZ6
854Please respect copyright.ＰＥＮＡＮＡ0JM4XI3778
不過好消息是，對抗D614品種的抗體，其對抗G614品種品種效率並無任何損傷。854Please respect copyright.ＰＥＮＡＮＡUCRzSYyS6i
854Please respect copyright.ＰＥＮＡＮＡDITtlecpPi
這亦即間接顯示出以D614品種作原材料的疫苗，其產生的抗體亦能有效對抗G614品種病毒，而事實上現今亦有疫苗是利用G614品種作原材料，奈何是鄰國出品。854Please respect copyright.ＰＥＮＡＮＡ1JUBt8ERJG
854Please respect copyright.ＰＥＮＡＮＡk4uhV4joUv
854Please respect copyright.ＰＥＮＡＮＡSiFdeFTkO0
（圖6）至於近來在挪威發現的新變種M439K品種，基於是新發現的關係，現時醫學界及學術界均無任何學術文章作詳細研究其特性。854Please respect copyright.ＰＥＮＡＮＡsnZJn2LOc2
854Please respect copyright.ＰＥＮＡＮＡgnupBq6IcI
854Please respect copyright.ＰＥＮＡＮＡoVtEsXsPPX
莫論病毒變種與否，只需一個乞嗤，病毒就已經不需近距離接觸，便能透過體液傳播至他人。854Please respect copyright.ＰＥＮＡＮＡ1KmubaoNLW
854Please respect copyright.ＰＥＮＡＮＡBlBxAqAnT9
將「新變種」及「不需近距離接觸」串連在一起的報導手法，有著混淆視聽的成份，並不可取。854Please respect copyright.ＰＥＮＡＮＡYlRhfpHP50
854Please respect copyright.ＰＥＮＡＮＡxXoANuhAD9
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。854Please respect copyright.ＰＥＮＡＮＡcEizx03RPo
854Please respect copyright.ＰＥＮＡＮＡFyjUfUthI4
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc854Please respect copyright.ＰＥＮＡＮＡSn5kuGHgOZ
854Please respect copyright.ＰＥＮＡＮＡMdbcGXfGYO
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。854Please respect copyright.ＰＥＮＡＮＡr0mtoZawEi
854Please respect copyright.ＰＥＮＡＮＡDv6Z5wj129
Link:854Please respect copyright.ＰＥＮＡＮＡ3R1UWJCZDf
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio854Please respect copyright.ＰＥＮＡＮＡ5Th0YfAu3R
854Please respect copyright.ＰＥＮＡＮＡbPZsM5CpX9
854Please respect copyright.ＰＥＮＡＮＡGGoB7sSPOS
有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。854Please respect copyright.ＰＥＮＡＮＡOQqAk9pOkA
854Please respect copyright.ＰＥＮＡＮＡU4xrAs3G3p
https://www.instagram.com/potatopigtongue/854Please respect copyright.ＰＥＮＡＮＡfno8GVR5Py
854Please respect copyright.ＰＥＮＡＮＡVzY5fqii2R
854Please respect copyright.ＰＥＮＡＮＡ6wtSdhSU9L
Ref1:https://www.nature.com/articles/s41586-020-2895-3854Please respect copyright.ＰＥＮＡＮＡS1T8uJCeVj