口腔所進食的食物，途經各器官後便會來到小腸，絕大部份的營養最終將透過空腸(Jejunum)進入血液循環系統裡頭，再分配予各身體細胞；850Please respect copyright.ＰＥＮＡＮＡVDcV0zPMfL
我們的空腸內壁擁有著絨毛狀的結構(villi)，將大大增加遇上及吸取營養的效率，以達其消化及吸收營養的重任。850Please respect copyright.ＰＥＮＡＮＡ8nPpSnv2fl
850Please respect copyright.ＰＥＮＡＮＡIiUhN484f3
850Please respect copyright.ＰＥＮＡＮＡxUQWGIEe53
850Please respect copyright.ＰＥＮＡＮＡlaVp7xVbqH
（圖2）食得是褔，著得是祿。850Please respect copyright.ＰＥＮＡＮＡVZpMD6cfMR
患有短腸症候群(Short Bowel Syndrome，每年約每一百萬個小童便有三名患者)或其他腸道疾病問題的兒童，因著空腸長度有機會出現過短的狀況，很多時候下並沒能夠吸取足夠營養支撐正常成長。850Please respect copyright.ＰＥＮＡＮＡaBnIjwAe5p
850Please respect copyright.ＰＥＮＡＮＡDWRds7Uk1i
850Please respect copyright.ＰＥＮＡＮＡMb65yH9Mjt
嚴重的情況，便需要進行器官移植。850Please respect copyright.ＰＥＮＡＮＡuKnWHFdGjO
850Please respect copyright.ＰＥＮＡＮＡ2QCePniPXl
只不過，適用的器官並不是話來就來，而且亦有不少個案出現器官排斥問題，引發一連串的併發症。850Please respect copyright.ＰＥＮＡＮＡxf0eNVlw9y
850Please respect copyright.ＰＥＮＡＮＡ4cobxosisg
（圖3）為了紓困現狀，有科學家在近日發表文章（Ref1)，嘗試提出方法解決現時所面對的困局–850Please respect copyright.ＰＥＮＡＮＡpildOoW43N
850Please respect copyright.ＰＥＮＡＮＡnUCPFSFlHF
抽取患者的腸道細胞，以體外的方式在實驗室進行培植，製造出新一條的空腸。850Please respect copyright.ＰＥＮＡＮＡVPdrHrOhid
而因著器官是由患者本身的細胞而來，出現排斥的機會亦順然大幅度能夠減低下來。850Please respect copyright.ＰＥＮＡＮＡsKqgrWvmtk
850Please respect copyright.ＰＥＮＡＮＡ0MLstBtfTh
850Please respect copyright.ＰＥＮＡＮＡu94yl3kYjo
850Please respect copyright.ＰＥＮＡＮＡ0vyGq09Ul0
這次研究中，他們找來了28名歲數從3個月大至15歲的小童，從某部份的病人體內拿取2mm左右的腸道樣本，在實驗室內培植兩個月左右的時間，得出俱備空腸功能的類器官850Please respect copyright.ＰＥＮＡＮＡCI5sVuWU9j
(Organoid);850Please respect copyright.ＰＥＮＡＮＡgYlisiU5su
850Please respect copyright.ＰＥＮＡＮＡ5QSIcO6hAa
類器官可看成為半完成物，有著器官的關鍵功能，但外貌及個別特徵始終與完整器官差天共地。850Please respect copyright.ＰＥＮＡＮＡEEPidfvdHM
850Please respect copyright.ＰＥＮＡＮＡZNRjhZx26g
同時間，他們亦拿取病人腸道一小節，把所有的細胞清除得一乾二淨，用作為日後移植用的基座(Scaffold)。850Please respect copyright.ＰＥＮＡＮＡxnOb7CRZLs
之所以要沿用病人的腸道作為基座，原因是病人腸道本質上有著引導類器官繼續發展成型的能力，而這種本質現今科技上還沒能完完全全利用其他物料成功複製出來。850Please respect copyright.ＰＥＮＡＮＡwW01wlYdhz
850Please respect copyright.ＰＥＮＡＮＡAB2YnBqBwH
他們把類器官培植在基座上一段時間後，再嘗試移植到老鼠身體上，箇中亦證實得到類器官在老鼠體內擁有發展成為腸道的能力。850Please respect copyright.ＰＥＮＡＮＡDaFUiBAQlD
850Please respect copyright.ＰＥＮＡＮＡHI4Lia4C2A
將類器官移植回到病人體內這一步，無疑還有一段距離才能實行。850Please respect copyright.ＰＥＮＡＮＡwUWMOESHK9
但這研究在老鼠身上所得出的成果，至少證實得到這個大方向是有著實際應用上的可行性，並非紙上談兵風花雪月，而是為日後實際套用在病人方面上奠下了一重要的理論基礎。850Please respect copyright.ＰＥＮＡＮＡxDMP52Qlnm
850Please respect copyright.ＰＥＮＡＮＡEAt5ZHw3XL
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。850Please respect copyright.ＰＥＮＡＮＡ450yjQ5aj6
850Please respect copyright.ＰＥＮＡＮＡBCnErchNJk
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc850Please respect copyright.ＰＥＮＡＮＡqAwdTPk70P
850Please respect copyright.ＰＥＮＡＮＡUpHAtlUGOb
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。850Please respect copyright.ＰＥＮＡＮＡ9uZn0N4ae6
850Please respect copyright.ＰＥＮＡＮＡPtFiHVWLV4
Link:850Please respect copyright.ＰＥＮＡＮＡMOyjV3Fkyl
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio850Please respect copyright.ＰＥＮＡＮＡQXbjw8QVb0
850Please respect copyright.ＰＥＮＡＮＡ9f1kU7I6Kp
850Please respect copyright.ＰＥＮＡＮＡihQzVBGF1r
有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。850Please respect copyright.ＰＥＮＡＮＡNFU7KqFOM7
850Please respect copyright.ＰＥＮＡＮＡTupQG8djkL
850Please respect copyright.ＰＥＮＡＮＡph3Dua9yz9
Ref1:https://www.nature.com/articles/s41591-020-1024-z850Please respect copyright.ＰＥＮＡＮＡai4VM7n79R
1234 copyright protection846ＰＥＮＡＮＡBtAwaTe5vo 尼

216.73.216.217