藥物的效用有時候因人而異，其中一道原因，可以歸究於每個人體內的腸道細菌品種有所不同所致。704Please respect copyright.ＰＥＮＡＮＡUvpuWWtSf1
704Please respect copyright.ＰＥＮＡＮＡjiZq4MCjYt
704Please respect copyright.ＰＥＮＡＮＡHla3y7DPkf
(圖2)口服藥物要抵達血管循環系統的話，無可避免將會途經我們的腸道。704Please respect copyright.ＰＥＮＡＮＡ3gOGYt1sU1
而我們腸道的細菌有能力改造或代謝藥物，因而改變藥物結構及其效用。704Please respect copyright.ＰＥＮＡＮＡXblk959Lit
704Please respect copyright.ＰＥＮＡＮＡJQ4v7wDVlW
704Please respect copyright.ＰＥＮＡＮＡY266jD1dEb
704Please respect copyright.ＰＥＮＡＮＡ0dpkjIo3xF
704Please respect copyright.ＰＥＮＡＮＡOLkeFLLpC2
(圖3)有科學家找來人體最為常見的76種腸道細菌品種，與271款不同界別常用的藥物共同放在一起12小時。704Please respect copyright.ＰＥＮＡＮＡsisGpVaVTA
704Please respect copyright.ＰＥＮＡＮＡwnorDVFubt
704Please respect copyright.ＰＥＮＡＮＡciCtF3XyFy
最終發現，271款藥物中，有多達176款藥物的濃度在被至少一種腸道細菌影響下，濃度減少了20%;704Please respect copyright.ＰＥＮＡＮＡLiOOVYrt8e
而這些腸道細菌品種每款可以代謝11-95款藥物不等。704Please respect copyright.ＰＥＮＡＮＡ7ka28LpzJb
704Please respect copyright.ＰＥＮＡＮＡ16sw5UcKgh
用上老鼠作動物模型，科學家更能找出所屬細菌哪一條基因負責消化/代謝藥物，引證腸道細菌影響藥物吸收的理念。704Please respect copyright.ＰＥＮＡＮＡIdQbUqonfz
704Please respect copyright.ＰＥＮＡＮＡfz1yog9vJM
倘若你腸道恰巧住有細菌A，而細菌A又有能力吸收你所口服的藥物，那麼藥效便有可能會大大減低。704Please respect copyright.ＰＥＮＡＮＡLt5TLpjgxv
704Please respect copyright.ＰＥＮＡＮＡncIPN13eHI
血液注射而非口服的藥物將有機會不受此限，因為藥物並不需一定要經過腸道裡頭。704Please respect copyright.ＰＥＮＡＮＡUHSR834AWX
704Please respect copyright.ＰＥＮＡＮＡFdel85WNE7
704Please respect copyright.ＰＥＮＡＮＡUxM6wqmIlb
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。704Please respect copyright.ＰＥＮＡＮＡWeSzeuhzjl
704Please respect copyright.ＰＥＮＡＮＡ8iQr6EkThZ
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc704Please respect copyright.ＰＥＮＡＮＡkhquXAtyDm
704Please respect copyright.ＰＥＮＡＮＡGf7T0GImsX
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。704Please respect copyright.ＰＥＮＡＮＡarzmT0LfSq
704Please respect copyright.ＰＥＮＡＮＡN0xYATg3K7
Link:704Please respect copyright.ＰＥＮＡＮＡ3d0fsdJcIz
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio704Please respect copyright.ＰＥＮＡＮＡcVwMiTsmV0
704Please respect copyright.ＰＥＮＡＮＡvBOCW1Zyak
704Please respect copyright.ＰＥＮＡＮＡGVD2t2yMIh
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。704Please respect copyright.ＰＥＮＡＮＡXQRqJzCa0S
704Please respect copyright.ＰＥＮＡＮＡoDM6jVIiMw
Ref1:https://www.nature.com/articles/s41586-019-1291-3704Please respect copyright.ＰＥＮＡＮＡ2alNIUT8wJ
1234 copyright protection700ＰＥＮＡＮＡFjK7vIy6Hs 尼

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