近日有急凍雞翼及其他產品被測量出擁有武肺存在，但武肺能否在雞翼或其他食物上大量繁殖呢？1210Please respect copyright.ＰＥＮＡＮＡ4TylZBZgmC
1210Please respect copyright.ＰＥＮＡＮＡ1WD71k3c9f
答案是，不可以。1210Please respect copyright.ＰＥＮＡＮＡgMEqJ8DmxF
1210Please respect copyright.ＰＥＮＡＮＡJgvldUhvQY
武肺進行大量繁殖的話，必需要借助活生生的細胞幫忙，而其中先決的一步就是要進入細胞體內。1210Please respect copyright.ＰＥＮＡＮＡUY3NzwVLYX
1210Please respect copyright.ＰＥＮＡＮＡocV274CiuB
武肺可否入侵細胞，基本上視乎可唔可以達成下列3個條件。1210Please respect copyright.ＰＥＮＡＮＡXKF87neOJ7
（圖1）1210Please respect copyright.ＰＥＮＡＮＡxstyWniBAz
1210Please respect copyright.ＰＥＮＡＮＡ3QzIjtbIS0
1210Please respect copyright.ＰＥＮＡＮＡd18b42rvK4
1. S protein與細胞表面的ACE2觸碰。1210Please respect copyright.ＰＥＮＡＮＡVTjqtVYD3z
1210Please respect copyright.ＰＥＮＡＮＡ0y2cTdDmeD
2. 細胞表面ACE2與S protein的形狀吻合，亦即是「啱嘴形」。1210Please respect copyright.ＰＥＮＡＮＡp5qzHYS1qn
1210Please respect copyright.ＰＥＮＡＮＡ3qBRpbwNzI
3. 細胞表面擁有TMPRSS2蛋白質，能夠對S protein進行切割。1210Please respect copyright.ＰＥＮＡＮＡtyXttLKb5J
1210Please respect copyright.ＰＥＮＡＮＡwZmrSfaCiO
滿足3大條件後，病毒就有能力能夠入侵細胞。1210Please respect copyright.ＰＥＮＡＮＡq1YN7KvJZT
當然，入侵細胞後還有很多因素決定武肺能否大量繁殖，但急凍雞翼連活生生的細胞也沒有，根本無可能可以大量繁殖。1210Please respect copyright.ＰＥＮＡＮＡ7VkqthMCsd
1210Please respect copyright.ＰＥＮＡＮＡLE28JjzZy7
何謂S protein和ACE2，可到我之前所寫的文章溫故知新。1210Please respect copyright.ＰＥＮＡＮＡbE6eZpFcMf
https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/issue/91210Please respect copyright.ＰＥＮＡＮＡozF1tYiKRb
1210Please respect copyright.ＰＥＮＡＮＡMd6dHk4qjA
1210Please respect copyright.ＰＥＮＡＮＡrHP0XSgtee
1210Please respect copyright.ＰＥＮＡＮＡfIPY6xcUEi
（圖2）1210Please respect copyright.ＰＥＮＡＮＡavAZdWGqHM
第二點所謂的「啱嘴型」，所指的就是ACE2的形狀能否與武肺的S protein形狀吻合，就好像砌Puzzle一樣，兩者不吻合的話就無法連結一起，勉強亦無幸福。1210Please respect copyright.ＰＥＮＡＮＡT8eKf7b77n
1210Please respect copyright.ＰＥＮＡＮＡ8tU5vLavs5
如圖中所見，正因為老鼠ACE2唔啱嘴型，所以武肺無法引致老鼠患上肺炎等病徵，袁教授等人因此亦改用啱嘴型的倉鼠作為武肺的動物實驗模型。1210Please respect copyright.ＰＥＮＡＮＡycchVTAIRc
1210Please respect copyright.ＰＥＮＡＮＡ2Cgz93Wo0S
（Ref 1)有科學家嘗試將武肺打落豬、雞和鴨身上，最終無法在牠們的任何器官身上找到武肺，而且亦沒有出現任何病徵，因此斷定牠們並不會受到武肺感染。1210Please respect copyright.ＰＥＮＡＮＡebgGHZbhwi
1210Please respect copyright.ＰＥＮＡＮＡDvoLsQg6Y7
1210Please respect copyright.ＰＥＮＡＮＡ3rHnNQWCbq
（圖3）1210Please respect copyright.ＰＥＮＡＮＡ8pYmlq94zh
關於第三點，肺(Lung)及腎臟(Kidney)同樣擁有一定數量的ACE2及TMPRSS2（Ref2)，因此將會成為武肺的主要針對對象。1210Please respect copyright.ＰＥＮＡＮＡGAAX9yMTPC
1210Please respect copyright.ＰＥＮＡＮＡ2LEHJ4mqkM
而心臟(Heart) 同樣擁有一定數量的ACE2，某程度亦解釋了為何武肺患者康復後會被發現心臟出現異樣。1210Please respect copyright.ＰＥＮＡＮＡGhwSYZKSx6
1210Please respect copyright.ＰＥＮＡＮＡTKgnU7BhoR
1210Please respect copyright.ＰＥＮＡＮＡi2iUjtt96q
而男性器官睪丸(Testis)，亦是ACE2數量較多的器官（圖中沒有列出），所以，嗯......1210Please respect copyright.ＰＥＮＡＮＡGJl2MpgnFu
1210Please respect copyright.ＰＥＮＡＮＡeUL2812fjr
1210Please respect copyright.ＰＥＮＡＮＡfMS0hHNXF2
1210Please respect copyright.ＰＥＮＡＮＡHTwowMCja4
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。1210Please respect copyright.ＰＥＮＡＮＡCk06bjLPWR
1210Please respect copyright.ＰＥＮＡＮＡSIWFWGAmju
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc1210Please respect copyright.ＰＥＮＡＮＡtKHoeGhsos
1210Please respect copyright.ＰＥＮＡＮＡvpPGKCPx4O
同時亦可以在Penana網站裡按「買一嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。1210Please respect copyright.ＰＥＮＡＮＡVkzpwPZFMR
1210Please respect copyright.ＰＥＮＡＮＡBlzLFFY0wj
Link:1210Please respect copyright.ＰＥＮＡＮＡD5Z3nfepEN
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio1210Please respect copyright.ＰＥＮＡＮＡxfrM7ygit9
1210Please respect copyright.ＰＥＮＡＮＡdAkfbgjmZC
1210Please respect copyright.ＰＥＮＡＮＡIxggQjkN64
有興趣接收科普資訊的話，歡迎follow IG: potatopigtongue。1210Please respect copyright.ＰＥＮＡＮＡLngyzjTzFm
1210Please respect copyright.ＰＥＮＡＮＡFCQW8xJ9LD
1210Please respect copyright.ＰＥＮＡＮＡHnqKz7LUdV
1210Please respect copyright.ＰＥＮＡＮＡ5CgXrgPXWk
1210Please respect copyright.ＰＥＮＡＮＡ7AUPD8bddx
1210Please respect copyright.ＰＥＮＡＮＡNB9kfIPkbt
Ref1:https://science.sciencemag.org/content/368/6494/10161210Please respect copyright.ＰＥＮＡＮＡZlOoNqybb5
1210Please respect copyright.ＰＥＮＡＮＡ05IlwogpYb
Ref2:https://www.sciencedirect.com/science/article/pii/S221323172030820X#fig11210Please respect copyright.ＰＥＮＡＮＡCjQd5yODL1
1234 copyright protection1206ＰＥＮＡＮＡtWsVZEkq3s 尼

216.73.216.217