科普專欄–薯不揀單 - 三十秒科學–身體細胞會否進行浪費舉動？

我們身體的細胞，會否作出多餘或者浪費的事情呢?760Please respect copyright.ＰＥＮＡＮＡIwobp7GQfd
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（圖2）超級簡化來說，我們細胞內含的粒線體能夠將我們所攝取的營養經由一系列的過程轉化成為ATP。760Please respect copyright.ＰＥＮＡＮＡgvFBmAfmyn
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ATP能夠為細胞提供所需的能源，我們的手腳之所以可以伸縮自如，全賴身體肌肉細胞等耗用ATP才能達成。760Please respect copyright.ＰＥＮＡＮＡJLacCr5p93
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（圖3）而唯獨在專門製造熱能的啡色脂肪細胞粒線體裡頭，內裡有一隻名為CKB(Creatine Kinase B)的蛋白酶會迅速透過Creatine將大量的ATP立刻轉回為ADP以及Phosphocreatine；760Please respect copyright.ＰＥＮＡＮＡRFdrC4NeSF
肌肉細胞及白色脂肪細胞雖然也會進行這步驟，但效率遠遠低於啡色脂肪細胞。760Please respect copyright.ＰＥＮＡＮＡigNQdx3IbT
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ADP並不是細胞通用的能量單位，辛辛苦苦將得來的ATP又轉回成為ADP，情形就如在中國大陸境內將辛苦得來的美金(ATP)轉換為人民幣(ADP)一樣，驟眼看起上來超級無謂及浪費。760Please respect copyright.ＰＥＮＡＮＡuk63BHtJqA
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雖然細胞可以透過Phosphocreatine及ADP轉化成為ATP及Creatine，但在咖色脂肪細胞裡頭，這情況在大部分的時間也沒有發生，正如大陸境內沒法能夠兌換人民幣(ADP)為美金(ATP)一樣。760Please respect copyright.ＰＥＮＡＮＡ0C2j2eVF2C
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理論上，身體細胞理應發展出一套非常完善的系統，不會做出多餘浪費的行為。760Please respect copyright.ＰＥＮＡＮＡEAqFLCP1bj
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而現時開始有證據顯示，這「浪費行為」相信能夠輔助啡色脂肪將營養轉化成為熱能，而非能量的儲存。760Please respect copyright.ＰＥＮＡＮＡgvtHREf1Cz
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若能夠完整地理解整個機制，或許可透過藥物影響肚腩（白色脂肪）的CKB蛋白酶含量，將肚腩脂肪逐一消耗成為熱能，達減肥之效。760Please respect copyright.ＰＥＮＡＮＡ2lpKaJi66f
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如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。760Please respect copyright.ＰＥＮＡＮＡkcFesANF35
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc760Please respect copyright.ＰＥＮＡＮＡJw7Hi2Uvns
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。760Please respect copyright.ＰＥＮＡＮＡ4lACMBbDUi
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https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio760Please respect copyright.ＰＥＮＡＮＡiryJrKWtYn
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除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。760Please respect copyright.ＰＥＮＡＮＡUiMK1aME7C
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Ref1:https://www.nature.com/articles/s41586-021-03221-y760Please respect copyright.ＰＥＮＡＮＡsCpHJvUIk2

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