根據一篇尚未接受同行審查的文章（Ref1)，Moderna及輝端疫苗兩者在人體所產生的抗體數量並無大分別，而且抗體所針對病毒的位置，亦跟自然感染武肺人士所產生的抗體相同。600Please respect copyright.ＰＥＮＡＮＡnF6dJjQuNj
600Please respect copyright.ＰＥＮＡＮＡH0TkhVZm3m
注射兩者第二劑疫苗的3-14星期後，其抗體數量約與自然感染人士1.3個月後的數量接近。600Please respect copyright.ＰＥＮＡＮＡlHaFhOXvfM
600Please respect copyright.ＰＥＮＡＮＡVrzxjpNjxi
奈何的是，疫苗所產生的抗體，其應對英國/南非變種的能力明顯有所銳弱。根據抗體種類的不同，有一些抗體應對變種病毒的能力至少被銳弱了十倍以上有多。600Please respect copyright.ＰＥＮＡＮＡI3eRH7XCiT
600Please respect copyright.ＰＥＮＡＮＡ4VC1LzsMRB
同時間，把武肺病毒與疫苗抗體共同培植的話，能生存下來的武肺病毒亦出現與英國及南非變種一樣的排序，變相逆向證明疫苗或自然感染未變種病毒人士的抗體沒能有效應對最新的南非/英國或旗下牽伸的各種變種。600Please respect copyright.ＰＥＮＡＮＡpGP367o5ex
600Please respect copyright.ＰＥＮＡＮＡACXf878i2P
若然屬實，Moderna/輝端疫苗很有可能要更新第二代作出應對。600Please respect copyright.ＰＥＮＡＮＡCDOwCyq88S
600Please respect copyright.ＰＥＮＡＮＡnPdPiRPkeC
至於科興及國藥疫苗會否同屬一命運，則尚未清楚，但在理論層面上，滅活疫苗應對變種的可能性會較mRNA疫苗更高。600Please respect copyright.ＰＥＮＡＮＡOEKVbOdaKz
600Please respect copyright.ＰＥＮＡＮＡzzFy8kbRBZ
不過理論歸理論，一切尚需實驗證據確實。600Please respect copyright.ＰＥＮＡＮＡg8dIjRDMPl
600Please respect copyright.ＰＥＮＡＮＡM1Uo3hbOUo
600Please respect copyright.ＰＥＮＡＮＡMqPDVTd4fS
600Please respect copyright.ＰＥＮＡＮＡEb6ZDKBqtt
Ref1:https://www.biorxiv.org/content/10.1101/2021.01.15.426911v1.full.pdf600Please respect copyright.ＰＥＮＡＮＡdhApiW1dB5
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科普專欄–薯不揀單
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科普專欄–薯不揀單
Author:
薯仔聞茱莉
薯仔聞茱莉
ISSUE #141
Moderna及輝瑞疫苗對抗英國及南非的武肺變種能力
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