科普專欄–薯不揀單 - 深入淺出–流感疫苗的重要發展

季節性流感造成全球每年約290,000-650,000人的死亡。801Please respect copyright.ＰＥＮＡＮＡKcf7quA1oR
801Please respect copyright.ＰＥＮＡＮＡ4qPOVzzZDc
801Please respect copyright.ＰＥＮＡＮＡ8mDjpeo2VY
流感病毒接近每年均會出現變種，基於現時並無統一疫苗對抗各品種，所以很多時候在翌年便要轉換對應的疫苗。801Please respect copyright.ＰＥＮＡＮＡJKUq1UdZxX
801Please respect copyright.ＰＥＮＡＮＡTchCIzXaCH
(圖2)流感病毒外部、名為HA的部份，將主宰病毒能否進入人體細胞裡頭。801Please respect copyright.ＰＥＮＡＮＡIQcgW0uPnK
801Please respect copyright.ＰＥＮＡＮＡ9EFChNow05
801Please respect copyright.ＰＥＮＡＮＡLTV1mWb9lI
流感病毒的變異較常出現在頭部位置(Head)，而現時疫苗的設計亦主要針對HA的頭部位置。801Please respect copyright.ＰＥＮＡＮＡfDcHnFNbKK
801Please respect copyright.ＰＥＮＡＮＡduIYhxYapV
其目標是希望人們注射疫苗後，體內會產生對應HA頭部位置的抗體，阻止病毒進入人體細胞繼而作惡。801Please respect copyright.ＰＥＮＡＮＡBxgXOZwuZB
801Please respect copyright.ＰＥＮＡＮＡraNMawPfyi
(圖3)另一方面來想，流感病毒變種就如不同顏色的花朵一樣。801Please respect copyright.ＰＥＮＡＮＡmLXJ6zme1Z
801Please respect copyright.ＰＥＮＡＮＡzLky00jkWi
801Please respect copyright.ＰＥＮＡＮＡooxA5gxAgG
雖然花朵各有不同，但莖部位置則大同小異。801Please respect copyright.ＰＥＮＡＮＡK7M3QEPQNJ
801Please respect copyright.ＰＥＮＡＮＡUVKHIRlZ9U
(圖4)基於Stalk位置(花朵莖部位置)的變異成數較細，現時科學家正研發針對Stalk位置的疫苗(Ref1)，希望可以透過一款疫苗對抗多款流感變種。801Please respect copyright.ＰＥＮＡＮＡerUHaZFt4t
801Please respect copyright.ＰＥＮＡＮＡaJvlA7VkRO
801Please respect copyright.ＰＥＮＡＮＡpIknttKTrf
這類型的疫苗現時已進入Phase1狀態，人體試驗找來了51名人士，注射疫苗後體內亦得出相應的大量抗體。801Please respect copyright.ＰＥＮＡＮＡy5yWYD7WRt
801Please respect copyright.ＰＥＮＡＮＡdalw0Buura
而日後所進行的人體試驗，將會能夠獲取資料測量疫苗能否達到預防流感之效。801Please respect copyright.ＰＥＮＡＮＡukqKtSiqR4
801Please respect copyright.ＰＥＮＡＮＡx4EV38oree
若安全性、效率等等均達到合理水平的話，將來不但之可以不用經常轉換疫苗款式，亦能大大減低疫苗與當下流感款式不吻合的機會，皆大歡喜。801Please respect copyright.ＰＥＮＡＮＡK57WgSmKTp
801Please respect copyright.ＰＥＮＡＮＡxj9gsRhK4T
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。801Please respect copyright.ＰＥＮＡＮＡrTVVPmSJAf
801Please respect copyright.ＰＥＮＡＮＡes6parRfkI
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc801Please respect copyright.ＰＥＮＡＮＡ8LurX3DIc8
801Please respect copyright.ＰＥＮＡＮＡYteqFDErlr
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。801Please respect copyright.ＰＥＮＡＮＡj6AKYcwndq
801Please respect copyright.ＰＥＮＡＮＡoEeX7uCH5X
Link:801Please respect copyright.ＰＥＮＡＮＡEThMK0wANb
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio801Please respect copyright.ＰＥＮＡＮＡpj7aQxe5AB
801Please respect copyright.ＰＥＮＡＮＡXM48q8mnKf
有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。801Please respect copyright.ＰＥＮＡＮＡLH9NqhUgcB
801Please respect copyright.ＰＥＮＡＮＡtfmvtG5SdN
https://www.instagram.com/potatopigtongue/801Please respect copyright.ＰＥＮＡＮＡkc9cPFHj3Y
801Please respect copyright.ＰＥＮＡＮＡSYyqbsNxyE
801Please respect copyright.ＰＥＮＡＮＡAPRNkaV43C
Ref1:https://www.nature.com/articles/s41591-020-1118-7801Please respect copyright.ＰＥＮＡＮＡmMBWlnSXnX

ns3.16.161.16da2

介面主題:

字體大小:

行距:

段距:

自動加載下一章