大部份的人體細胞均會藏有油脂。當細胞需要能源的時候,油脂可以在粒線體裡頭分解成為能源。876Please respect copyright.PENANAG9Q3cuGCVk
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(圖2)有科學家發現(Ref1),當有細菌入侵細胞的時候,細胞的油脂數量會增加,但相應的體積亦會有所縮小。876Please respect copyright.PENANAwZHYFJm54L
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(圖3)油脂除了能量儲存功用外,亦提供了各種蛋白質聚集的地方。876Please respect copyright.PENANAiagISwYfyk
譬如說,PLN5就是一種引領油脂抵達粒線體的蛋白質。876Please respect copyright.PENANAbjf1cGMDPB
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科學家在文中指出,當有細菌入侵細胞的時候,油脂上的PLN5蛋白質就會減少,取而代之會有各種與免疫系統有關的蛋白質黏附在油脂上,並傾向與細菌接觸。876Please respect copyright.PENANABZLYZQhXjW
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箇中油脂上其中一種名為Cathelicidin的蛋白質便有著破壞部份細菌的外壁功效。876Please respect copyright.PENANA4LLLKVjvf7
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(圖4)隨著油脂用作對付細菌的關係,油脂再也無瑕抵達粒線體作分解能源之用。因此在對抗入侵者期間,細胞亦會因而傾向轉用葡萄糖作為能量來源。876Please respect copyright.PENANAqdPFWnxQ89
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之於如何善用這種知識來研發對抗感染的療法,那將會是科學家們日後的命題。876Please respect copyright.PENANABrtuU6rdtU
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如果想我快啲出文的話,請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark,這對我非常之重要。876Please respect copyright.PENANAav6Z6f1D1t
876Please respect copyright.PENANAh21Ke50NbT
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc876Please respect copyright.PENANAfIWRvF1hTC
876Please respect copyright.PENANAXmwEHHQkV6
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」,以課金的方式推動我繼續搜羅資料寫文,多謝。876Please respect copyright.PENANAxBNmRcKxsv
876Please respect copyright.PENANAHxEDn9eLPr
Link:876Please respect copyright.PENANAyNcFMNTXdI
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio876Please respect copyright.PENANAMaykPh9Wqh
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有興趣接收科學資訊的話,歡迎follow IG: potatopigtongue。876Please respect copyright.PENANAMhPyK9MMGh
876Please respect copyright.PENANA0WUjX3GUaa
Ref1:https://science.sciencemag.org/content/370/6514/eaay8085876Please respect copyright.PENANA9tAkntBpY0
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科普專欄–薯不揀單
Author:
薯仔聞茱莉
ISSUE #81
深入淺出–油脂在細胞裡的功用
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