科普專欄–薯不揀單 - 三十秒科學–頭髮幹細胞的三個階段

頭髮一直也是不少人所關注的議題，而頭髮的生長，實情跟幹細胞(Stem cell)息息相關。529Please respect copyright.ＰＥＮＡＮＡQGBCSPgdVH
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（圖2）頭髮的生長，是由位於髮囊底部名為hair-follicle stem cells (HFSCs)的幹細胞產生出來。529Please respect copyright.ＰＥＮＡＮＡ7TgN8aEwuq
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這些幹細胞會不斷地進行三個階段的循環，分別為anagen、catagen以及telogen。529Please respect copyright.ＰＥＮＡＮＡCshLi7ilcn
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（圖3）當anagen發生的時候，HFSCs幹細胞就會開始進行自我複製，經一系列的程序後便會導致毛髮生長;這階段可持續進行數年。529Please respect copyright.ＰＥＮＡＮＡZ8eE6htDcF
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而當到達catagen的時候，毛髮便會停止生長，但依舊維持原位。529Please respect copyright.ＰＥＮＡＮＡVx4DUKrMXc
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之後便會進入telogan階段， HFSCs幹細胞進入「冬眠」狀態，不作任何複製舉動，而毛髮亦會因而自然地脫落。529Please respect copyright.ＰＥＮＡＮＡTef2zjNKO6
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落入telogan階段後，幹細胞便會再度進入anagen階段，重新開始產生毛髮。529Please respect copyright.ＰＥＮＡＮＡg99RLtX9WY
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健康人士的HFSCs幹細胞，高達80-90%處於anagen，10-20%處於catagan，只有1-5%處於telogan階段。529Please respect copyright.ＰＥＮＡＮＡMwKk5Gw1ef
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由此可以推想出，脫髮或者禿頭的原因就是大多數的HFSCs處於catagan或telogan階段，並不再重返anagen階段。529Please respect copyright.ＰＥＮＡＮＡpGuh9m9WUT
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下集將會講解為何壓力過大會導致脫髮，箇中的原理涉及荷爾蒙的改變，及幹細胞三階段的失衡。529Please respect copyright.ＰＥＮＡＮＡMbt0f3EkaR
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如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。529Please respect copyright.ＰＥＮＡＮＡ8WjzYN3Eue
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc529Please respect copyright.ＰＥＮＡＮＡQjQ0762mZu
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。529Please respect copyright.ＰＥＮＡＮＡZbQ5Y0xwmA
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https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio529Please respect copyright.ＰＥＮＡＮＡWMVjM2qjRf
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除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。529Please respect copyright.ＰＥＮＡＮＡsrlLSAOjC3
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Ref1:https://pubmed.ncbi.nlm.nih.gov/26763421/529Please respect copyright.ＰＥＮＡＮＡ9QzhNSa0XD

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