科普專欄–薯不揀單 - 三十秒科學–頭髮幹細胞的三個階段

頭髮一直也是不少人所關注的議題，而頭髮的生長，實情跟幹細胞(Stem cell)息息相關。623Please respect copyright.ＰＥＮＡＮＡni8IVj0BZJ
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（圖2）頭髮的生長，是由位於髮囊底部名為hair-follicle stem cells (HFSCs)的幹細胞產生出來。623Please respect copyright.ＰＥＮＡＮＡvTkWInbCtF
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這些幹細胞會不斷地進行三個階段的循環，分別為anagen、catagen以及telogen。623Please respect copyright.ＰＥＮＡＮＡQxCDCbOeH4
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（圖3）當anagen發生的時候，HFSCs幹細胞就會開始進行自我複製，經一系列的程序後便會導致毛髮生長;這階段可持續進行數年。623Please respect copyright.ＰＥＮＡＮＡE7rSTejuF7
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而當到達catagen的時候，毛髮便會停止生長，但依舊維持原位。623Please respect copyright.ＰＥＮＡＮＡWbwKQtliHB
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之後便會進入telogan階段， HFSCs幹細胞進入「冬眠」狀態，不作任何複製舉動，而毛髮亦會因而自然地脫落。623Please respect copyright.ＰＥＮＡＮＡriIBemyJzq
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落入telogan階段後，幹細胞便會再度進入anagen階段，重新開始產生毛髮。623Please respect copyright.ＰＥＮＡＮＡCjsmTtH9XX
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健康人士的HFSCs幹細胞，高達80-90%處於anagen，10-20%處於catagan，只有1-5%處於telogan階段。623Please respect copyright.ＰＥＮＡＮＡaC4C2qtM8M
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由此可以推想出，脫髮或者禿頭的原因就是大多數的HFSCs處於catagan或telogan階段，並不再重返anagen階段。623Please respect copyright.ＰＥＮＡＮＡeuOFJfaosH
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下集將會講解為何壓力過大會導致脫髮，箇中的原理涉及荷爾蒙的改變，及幹細胞三階段的失衡。623Please respect copyright.ＰＥＮＡＮＡZPG20s63Cl
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如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。623Please respect copyright.ＰＥＮＡＮＡ0HyJ5bUlBd
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc623Please respect copyright.ＰＥＮＡＮＡEJQHQq0WVy
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。623Please respect copyright.ＰＥＮＡＮＡHfq6wQbQdn
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Link:623Please respect copyright.ＰＥＮＡＮＡVopYGxTzm4
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio623Please respect copyright.ＰＥＮＡＮＡr0hE5vVLgp
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除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。623Please respect copyright.ＰＥＮＡＮＡqxEUsvkZrd
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Ref1:https://pubmed.ncbi.nlm.nih.gov/26763421/623Please respect copyright.ＰＥＮＡＮＡ9hHFet80aY

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