上集link: 三十秒科學–被切除90%還有能力回復正常形狀及功能的器官894Please respect copyright.PENANAI6voUf2XWp
https://lih.kg/2433238894Please respect copyright.PENANAB6u0UDdEzi
894Please respect copyright.PENANAYjhVRBSJQC
894Please respect copyright.PENANA2Bd242ufN9
撇除皮膚的話,肝臟是我們身體最大的器官。894Please respect copyright.PENANAqcRNBL2fyB
除再生能力強大之外,肝臟的另外一個特點就是會與我們的體型成正比關係。894Please respect copyright.PENANAD4IVVrI1Eh
894Please respect copyright.PENANA8lshFWjJav
(圖2)肝臟細胞根據其所在位置,共可分為三個區域(Zone)。894Please respect copyright.PENANA1TG1lLdLXW
894Please respect copyright.PENANAUTsrPy5kef
894Please respect copyright.PENANALz1SBM22Mh
三個區域的肝臟細胞在新陳代謝及基因表達上均有顯著的分別。894Please respect copyright.PENANATk3pRJnc8W
譬如說Zone1細胞所獲得的氧氣量比Zone3的為高,Zone1細胞製糖的能力比Zone3的為強。894Please respect copyright.PENANAJFe5DQPwoG
894Please respect copyright.PENANAQn0QOprdNG
(圖3)在正常情況下,Zone1的肝臟細胞會一直在減少,並由Zone2的細胞繁殖補回所失去的數量,而Zone3的細胞數量則相對上不會有太大變化。894Please respect copyright.PENANA4TS2zvfM7E
894Please respect copyright.PENANAgLmX6yIhlR
894Please respect copyright.PENANALNSjH2vAOo
(圖4)當Zone3區域細胞受損的話,Zone1及2區域細胞便會一起繁殖,填補所失去的細胞。894Please respect copyright.PENANAFrtd9yTCzs
反之,當Zone1區域細胞受損的話,Zone2及3區域細胞便會一起繁殖,對其作出填補。894Please respect copyright.PENANAjNVHvRkrFj
894Please respect copyright.PENANAcmKk7LjsCD
894Please respect copyright.PENANAnnnfL0MQFa
若果Zone1、2、3細胞一起受損的話,根據老鼠實驗指出(Ref2),開頭時份將會由Zone1的細胞主導繁殖,數量到達一定程度後,Zone2區域的細胞便會出手幫忙,而Zone3區域細胞在整個回復的過程中所參與的比例則全程偏低。894Please respect copyright.PENANA4P7mcc2Oec
894Please respect copyright.PENANA22SdVkzt0z
894Please respect copyright.PENANAzWWvoFCKQT
如果想我快啲出文的話,請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark,這對我非常之重要。894Please respect copyright.PENANAsP14KhPIBp
894Please respect copyright.PENANADs3oSfbPWs
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc894Please respect copyright.PENANA9m9Vd7mPLM
894Please respect copyright.PENANA7t4jecXjkj
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」,以課金的方式推動我繼續搜羅資料寫文,多謝。894Please respect copyright.PENANASY6JbPfIwm
894Please respect copyright.PENANA22Sn8uuqwT
Link:894Please respect copyright.PENANA2GfYfKI0i8
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio894Please respect copyright.PENANABb1K3X5Tdr
894Please respect copyright.PENANAl7Zdoimyqs
894Please respect copyright.PENANA9erXv4eTYc
除非Facebook及IG重開侵侵的account,否則我的IG將不會再作更新,只會寄居本土LIHKG及Penana。894Please respect copyright.PENANAuj5oivoqOQ
894Please respect copyright.PENANAKiiZaNZWe3
Ref1:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387900/894Please respect copyright.PENANAR6ohC5oljZ
Ref2:https://science.sciencemag.org/content/371/6532/eabc4346894Please respect copyright.PENANAGQxHOK5bCG
Ref3:https://pubmed.ncbi.nlm.nih.gov/18600221/894Please respect copyright.PENANApduIs0ocld
Ref4:https://www.ncbi.nlm.nih.gov/books/NBK421/894Please respect copyright.PENANAvQgl5ksFD1
Ref5:https://science.sciencemag.org/content/371/6532/887894Please respect copyright.PENANAsBOqCjZFJt
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科普專欄–薯不揀單
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科普專欄–薯不揀單
Author:
薯仔聞茱莉
ISSUE #172
三十秒科學–肝臟細胞共可分為三個區域
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