前列腺癌與正常前列腺細胞的其中一道不同之處,就是前列腺癌細胞裡頭含有豐盛的油脂粒(Lipid Droplet)。265Please respect copyright.PENANAR7fEb1Mqic
265Please respect copyright.PENANARIKFUEZ1rg
265Please respect copyright.PENANAGQW9CqxDMr
油脂粒為細胞儲存脂肪的一道地方,在不少癌症例如乳癌、腸癌及腦癌也能找得到數量充盛的油脂粒。265Please respect copyright.PENANAXxpjrjKMTa
265Please respect copyright.PENANAnm2IacXRSM
(圖2)前列腺癌細胞油脂粒的主要成份,是名為Cholesteryl ester (CE)的物質,265Please respect copyright.PENANADflb4mQnh5
簡單來說可以看成為脂肪酸與膽固醇結合在一起的物質。265Please respect copyright.PENANAFGG6ui4JPu
265Please respect copyright.PENANAZUblh39rbF
265Please respect copyright.PENANAl051iW9dpu
(圖3)CE,亦即是前列腺癌細胞油脂粒的主要成份,是依靠細胞裡頭一隻名為ACAT的蛋白酶製作而成。265Please respect copyright.PENANAiXtgvNzvHh
265Please respect copyright.PENANAeTYUJi2Mqr
265Please respect copyright.PENANA90myFWFzRY
利用抑壓ACAT的藥物不但之能夠將老鼠的前列腺腫瘤縮小,更對老鼠身體的其他器官及細胞並無做成任何大的影響。265Please respect copyright.PENANAQ1Khywg4Zl
265Please respect copyright.PENANAjtP34VGilZ
某部份的前列腺癌細胞可依靠抑壓雄激素來阻止其生長,但此方法並非絕對有效,某部份的前列腺癌細胞並不依賴雄激素亦能快速生長及轉移到骨頭等各身體部位。265Please respect copyright.PENANAQ2g4RsD2uu
265Please respect copyright.PENANArUJDE7TBqZ
在這種情況下,針對前列腺癌細胞的油脂新陳代謝來抑壓其生長,未嘗不是一道可行的方向。265Please respect copyright.PENANAn5iqya3kpI
265Please respect copyright.PENANAi1aD5aIiuX
265Please respect copyright.PENANAFdDFHBOjKm
265Please respect copyright.PENANAiM530ivTBG
如果想我快啲出文的話,請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark,這對我非常之重要。265Please respect copyright.PENANAAoisF9BvIg
265Please respect copyright.PENANAxsOUcmpfu6
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc265Please respect copyright.PENANALebUOZY12I
265Please respect copyright.PENANAxY5pjUxqqp
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」,以課金的方式推動我繼續搜羅資料寫文,多謝。265Please respect copyright.PENANALPonjwA4XO
265Please respect copyright.PENANA0PuEQzexOJ
Link:265Please respect copyright.PENANA5wPaKOR6Wy
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio265Please respect copyright.PENANAP483GwAzTt
265Please respect copyright.PENANACpw5NRCl4j
265Please respect copyright.PENANAZ191qV3Qhs
基於WhatsApp/Facebook等問題,IG將不會再作更新,只會寄居本土LIHKG及Penana。265Please respect copyright.PENANAhJ3ir57it6
265Please respect copyright.PENANAHd0pHaWGxi
Ref1:https://pubmed.ncbi.nlm.nih.gov/24606897/265Please respect copyright.PENANAmSEm3bWxLf
arrow_back
科普專欄–薯不揀單
more_vert
-
info_outline Info
-
toc Table of Contents
-
share Share
-
format_color_text Display Settings
-
exposure_plus_1 Recommend
-
Sponsor
-
report_problem Report
-
account_circle Login
Search stories, writers or societies
Continue ReadingClear All
What Others Are ReadingRefresh
X
Never miss what's happening on Penana!
科普專欄–薯不揀單
Author:
薯仔聞茱莉
ISSUE #155
三十秒科學–癌細胞裡頭的油脂粒
LIKES 2
READS 261
BOOKMARKS 148
campaign
Request update 0
Sponsor
Login with Facebook
or Sign up/Login to comment or bookmark!
Click to load the next chapter
X
After each update request, the author will receive a notification!
smartphone100 → Request update
X
Sponsor again
Click to login
Login first to show your name as a sponsor.
Thank you for supporting the story! :)
Please Login first.
×
Write down what you like about the story
×
Reading Theme:
Font Size:
Line Spacing:
Paragraph Spacing:
Load the next issue automatically
Reset to default
×
People Who Like This