科普專欄–薯不揀單 - 深入淺出–用西醫科學角度審視中藥藥材(1)

中藥與西藥的比拼經常出現，箇中經常出現的論據就是中藥缺乏科學精密驗證，純粹是依靠經驗及神農嘗百草的方式積聚理論。428Please respect copyright.ＰＥＮＡＮＡsE8PVotpJP
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本篇文章無意將中藥及西藥對衡，而是嘗試以西醫科學角度審視一款中醫藥材，三七。428Please respect copyright.ＰＥＮＡＮＡXxVkTgZpMB
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（圖2）左圖為Panax notoginseng（三七）；428Please respect copyright.ＰＥＮＡＮＡmJuQCJDctq
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中圖為Sedum aizoon（土三七）；428Please respect copyright.ＰＥＮＡＮＡQ2ImMA5LLU
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而右圖則為Gynura japonica，頻繁被誤當成土三七的藥材。428Please respect copyright.ＰＥＮＡＮＡYOByuJ2UU3
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（圖3）不幸的是，這款誤當成土三七的藥材內含名為pyrrolizidine alkaloids (PAs)的化學物；428Please respect copyright.ＰＥＮＡＮＡ0L2YQgxs1F
真正的三七及土三七並不含PAs。428Please respect copyright.ＰＥＮＡＮＡHtpGLSkKit
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這些PA化學物進入人體後，會形成DHPA及DHP化學物。428Please respect copyright.ＰＥＮＡＮＡ56bYEFM4sw
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而DHPA及DHP化學物會與肝臟內各種蛋白質結合，導致肝臟無法運作正常。428Please respect copyright.ＰＥＮＡＮＡIfvkh0X4yP
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根據資料統計(Ref1)，誤當Gynura japonica作為土三七下藥，構成了中國在2017年約10-30%因攝取藥物導致肝臟收損的個案。428Please respect copyright.ＰＥＮＡＮＡbXmobqQdki
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這亦表示，若有經驗不足的中藥醫師或商人胡亂購買藥材的話，將會無意之間害了別人。428Please respect copyright.ＰＥＮＡＮＡji8EwewKdY
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能否有系統分配及管理中藥藥材的類別，將會是現今中醫所需面對的問題。428Please respect copyright.ＰＥＮＡＮＡNmFWbuMOw3
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有興趣繼續觀看用西醫角度觀看中藥的話，請給予正評及留言，反應熱烈的話將會寫新一集。428Please respect copyright.ＰＥＮＡＮＡe1TWDbDcKD
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如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。428Please respect copyright.ＰＥＮＡＮＡPUrgkWicYn
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc428Please respect copyright.ＰＥＮＡＮＡzsKt45d0AN
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。428Please respect copyright.ＰＥＮＡＮＡjrs9IPstWn
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Link:428Please respect copyright.ＰＥＮＡＮＡoKA6TDi1lW
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio428Please respect copyright.ＰＥＮＡＮＡqQSCBguQlg
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有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。428Please respect copyright.ＰＥＮＡＮＡYmLt56aVQf
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https://www.instagram.com/potatopigtongue/428Please respect copyright.ＰＥＮＡＮＡkqaAJPnW5T
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Ref1:https://www.nature.com/articles/s41401-020-00553-9428Please respect copyright.ＰＥＮＡＮＡc4pxuD1pDO