上集:三十秒科學–Natural Killer Cell543Please respect copyright.ＰＥＮＡＮＡRYJjECCFbt
- 分享自 LIHKG 討論區543Please respect copyright.ＰＥＮＡＮＡeoSTWunTXq
https://lih.kg/2548724543Please respect copyright.ＰＥＮＡＮＡSMv2BQ6g1j
543Please respect copyright.ＰＥＮＡＮＡKLazXnY9QU
上集提及過NK cell有著殺滅癌細胞的本領，如圖中所見，紅色的NK cell遇上綠色的癌細胞後，在1小時打後可以見得到癌細胞開始變形，更在74分鐘打後「灰飛煙滅」。543Please respect copyright.ＰＥＮＡＮＡgLlyKlAwg8
543Please respect copyright.ＰＥＮＡＮＡ9DO7EmjiJC
既然這麼順利，那為何還會有癌症出現呢?543Please respect copyright.ＰＥＮＡＮＡMZV5LTlKQf
543Please respect copyright.ＰＥＮＡＮＡSlgRGgDO08
(圖2)這是因為癌細胞有著各樣的手段對抗NK cell的襲擊，明哲保身。543Please respect copyright.ＰＥＮＡＮＡnKvGOMThUM
543Please respect copyright.ＰＥＮＡＮＡxioxfUkJFH
543Please respect copyright.ＰＥＮＡＮＡ5Pz1lV8lKx
從圖中的例子可以看到，這一次NK cell與癌細胞接觸約36分鐘後，不但沒有襲擊癌細胞，更以那兩名香港警察先鋒對待721的方式逃逸離去，使癌細胞得以安然無恙活下去。543Please respect copyright.ＰＥＮＡＮＡD2FlpAsDMy
543Please respect copyright.ＰＥＮＡＮＡ3vquviWJKh
(圖3)科學家發現，較能對抗NK cell的癌細胞有著一道應付NK cell的本領，它們遇上NK cell後會快速改變自身的蛋白質結構，將歸納名為actin的蛋白質速速調配至與NK cell的接觸點，形成圖中綠色區域的聚集。543Please respect copyright.ＰＥＮＡＮＡsiTzWWEd6V
543Please respect copyright.ＰＥＮＡＮＡjgMWDuCzvr
543Please respect copyright.ＰＥＮＡＮＡFZejmh9WOg
這些actin蛋白質的調動，促使抑制NK cell的蛋白質大量且集中聚積到與NK cell的接觸點(上集所指的 – 號組合)，導致NK cell失去殺滅癌細胞的功能，並且與癌細胞作出脫離。543Please respect copyright.ＰＥＮＡＮＡzC9aOJnUHI
543Please respect copyright.ＰＥＮＡＮＡdKafPw1DsO
而沒能對抗NK cell的癌細胞並沒有出現actin蛋白質的調整，相對上因而較易遭受到NK cell的侵襲。543Please respect copyright.ＰＥＮＡＮＡLGUg0c8wwx
543Please respect copyright.ＰＥＮＡＮＡyX1fTGWQyx
543Please respect copyright.ＰＥＮＡＮＡ9acIuUNmhg
543Please respect copyright.ＰＥＮＡＮＡwzwDwKdChG
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。543Please respect copyright.ＰＥＮＡＮＡjtO7lb98ZO
543Please respect copyright.ＰＥＮＡＮＡEbZMtIfX1E
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc543Please respect copyright.ＰＥＮＡＮＡsNoZDCCpBQ
543Please respect copyright.ＰＥＮＡＮＡ3wb6SWAmdQ
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。543Please respect copyright.ＰＥＮＡＮＡtHrGQiD73y
543Please respect copyright.ＰＥＮＡＮＡ5rnq42T3ck
Link:543Please respect copyright.ＰＥＮＡＮＡTdeY0G0V60
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio543Please respect copyright.ＰＥＮＡＮＡjar4kWoboa
543Please respect copyright.ＰＥＮＡＮＡRfY08rznp8
543Please respect copyright.ＰＥＮＡＮＡgiUpW66pN5
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。543Please respect copyright.ＰＥＮＡＮＡH0CwhhBxkk
543Please respect copyright.ＰＥＮＡＮＡOWH7fnDkbT
Ref1:https://cancerres.aacrjournals.org/content/78/19/5631543Please respect copyright.ＰＥＮＡＮＡsDQum1yzSI
8964 copyright protection539ＰＥＮＡＮＡKs6ZaTThrP 維尼

18.219.241.228