上集:三十秒科學–Natural Killer Cell579Please respect copyright.ＰＥＮＡＮＡjZuUW9PFzN
- 分享自 LIHKG 討論區579Please respect copyright.ＰＥＮＡＮＡyMCKUSXZYr
https://lih.kg/2548724579Please respect copyright.ＰＥＮＡＮＡtL3fh10OmX
579Please respect copyright.ＰＥＮＡＮＡpIVOA4WVI7
上集提及過NK cell有著殺滅癌細胞的本領，如圖中所見，紅色的NK cell遇上綠色的癌細胞後，在1小時打後可以見得到癌細胞開始變形，更在74分鐘打後「灰飛煙滅」。579Please respect copyright.ＰＥＮＡＮＡjzjFfxHoon
579Please respect copyright.ＰＥＮＡＮＡozwBK9b8cy
既然這麼順利，那為何還會有癌症出現呢?579Please respect copyright.ＰＥＮＡＮＡCvfmC98IOm
579Please respect copyright.ＰＥＮＡＮＡESrdVyFHUk
(圖2)這是因為癌細胞有著各樣的手段對抗NK cell的襲擊，明哲保身。579Please respect copyright.ＰＥＮＡＮＡhWPatAcFzX
579Please respect copyright.ＰＥＮＡＮＡqyFuXBNif0
579Please respect copyright.ＰＥＮＡＮＡMbrQ3k5HM6
從圖中的例子可以看到，這一次NK cell與癌細胞接觸約36分鐘後，不但沒有襲擊癌細胞，更以那兩名香港警察先鋒對待721的方式逃逸離去，使癌細胞得以安然無恙活下去。579Please respect copyright.ＰＥＮＡＮＡhjVgQjiZFt
579Please respect copyright.ＰＥＮＡＮＡ4Z4lCmK0J1
(圖3)科學家發現，較能對抗NK cell的癌細胞有著一道應付NK cell的本領，它們遇上NK cell後會快速改變自身的蛋白質結構，將歸納名為actin的蛋白質速速調配至與NK cell的接觸點，形成圖中綠色區域的聚集。579Please respect copyright.ＰＥＮＡＮＡC5W278pDue
579Please respect copyright.ＰＥＮＡＮＡYtlNx4mlbp
579Please respect copyright.ＰＥＮＡＮＡmeqkqUO0nn
這些actin蛋白質的調動，促使抑制NK cell的蛋白質大量且集中聚積到與NK cell的接觸點(上集所指的 – 號組合)，導致NK cell失去殺滅癌細胞的功能，並且與癌細胞作出脫離。579Please respect copyright.ＰＥＮＡＮＡX0kqvnorUT
579Please respect copyright.ＰＥＮＡＮＡcoptHSJMLP
而沒能對抗NK cell的癌細胞並沒有出現actin蛋白質的調整，相對上因而較易遭受到NK cell的侵襲。579Please respect copyright.ＰＥＮＡＮＡ2ikBfVkqF7
579Please respect copyright.ＰＥＮＡＮＡKrEXBr1uAx
579Please respect copyright.ＰＥＮＡＮＡDtnNo6ZIUk
579Please respect copyright.ＰＥＮＡＮＡEfEs0X9eRg
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。579Please respect copyright.ＰＥＮＡＮＡzkXIfpIyHI
579Please respect copyright.ＰＥＮＡＮＡ6dDr14ceEJ
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc579Please respect copyright.ＰＥＮＡＮＡabru76eQtT
579Please respect copyright.ＰＥＮＡＮＡZPwaQA9neD
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。579Please respect copyright.ＰＥＮＡＮＡxse3oK2iXe
579Please respect copyright.ＰＥＮＡＮＡx0ui079GyF
Link:579Please respect copyright.ＰＥＮＡＮＡ85g1OqbHbZ
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio579Please respect copyright.ＰＥＮＡＮＡCobJ8et5n6
579Please respect copyright.ＰＥＮＡＮＡRpVd19bLTF
579Please respect copyright.ＰＥＮＡＮＡuNgRqIFx4f
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。579Please respect copyright.ＰＥＮＡＮＡBZmpCluEDn
579Please respect copyright.ＰＥＮＡＮＡyac1R9hXdn
Ref1:https://cancerres.aacrjournals.org/content/78/19/5631579Please respect copyright.ＰＥＮＡＮＡxUBVpqjMw8
8964 copyright protection575ＰＥＮＡＮＡcntZtEhPnl 維尼

216.73.216.30